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  1. Mar 18, 2019 · We report three forensic cases of death from acute alcohol poisoning due to inhibition of the respiratory centre and eventual asphyxia. Blood alcohol concentrations in the three fatalities were 5.28, 3.33 and 3.78 mg/mL, respectively. Lethal doses and blood alcohol concentrations showed differences between individuals.

  2. Feb 29, 2024 · The average annual number of deaths from excessive alcohol use among males increased by 25,244 (26.8%), from 94,362 deaths during 2016–2017 to 119,606 during 2020–2021 ( Table 2 ). Age-standardized death rates among males increased from 54.8 per 100,000 population during 2016–2017 to 55.9 during 2018–2019, and to 66.9 during 2020–2021.

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  4. Meta-analysis of alcohol-attributable fractions for 15 causes of fatal nontraffic injuries. a N: Total number of studies and data from states included for a given cause of fatal injury. b BAC ≥ 0.10 g/dL: Number of deaths where the involved decedent (or offender in homicide and child maltreatment cases) had Blood Alcohol Concentration (BAC ...

    • 10.1016/j.amepre.2022.03.025
    • 2022/08
  5. Oct 20, 2022 · Heavy alcohol users who cut back to moderate drinking can lower their top number in a blood pressure reading (systolic pressure) by about 5.5 millimeters of mercury (mm Hg) and their bottom number (diastolic pressure) by about 4 mm Hg. If you have high blood pressure, avoid alcohol or drink alcohol only in moderation.

    • Purpose
    • Recent Findings
    • Summary

    To examine the acute and chronic effects of alcohol on blood pressure (BP) and the incidence of hypertension. We discuss the most current understanding of the mechanisms underlining these effects and their associations with the putative cardioprotective effects of consumption of low-to-moderate amounts of alcoholic beverages.

    A recent meta-analysis confirmed findings of experimental studies, demonstrating an acute biphasic effect of ethanol on BP, decreasing up to 12 h of ingestion and increasing after that. This effect is mediated by vagal inhibition and sympathetic activation. A meta-analysis found that chronic consumption of alcoholic beverages was associated with a ...

    The evidence from investigations with various designs converge regarding the acute biphasic effect of ethanol on BP and the risk of chronic consumption on the incidence of hypertension, particularly for Blacks. These effects do not support the putative cardioprotective effect of consumption of low-to-moderate amounts of alcoholic beverages. Mechani...

  6. Mar 26, 2014 · On the other hand, heavy alcohol consumption is believed to be associated with adverse effects on the heart, including detrimental effects on blood pressure, fibrinolytic factors, and ventricular arrhythmias . Another major adverse effect of alcoholic beverages is their carcinogenicity.

  7. Heavy alcohol consumption over long periods of time can result in severe liver damage, including death of liver cells (i.e., hepatocytes). Two mechanisms—apoptosis and necrosis—can contribute to hepatocyte death.