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May 22, 2023 · Neither lupus nor scleroderma has a cure, but treatment can help control symptoms and protect organs from damage. Those with scleroderma who only have a few hardened patches of skin may respond ...
Jun 15, 2024 · Digestive complications of scleroderma can include heartburn and difficulty swallowing. Scleroderma also can cause bouts of cramps, bloating, constipation or diarrhea. Some people who have scleroderma also may have problems absorbing nutrients due to overgrowth of bacteria in the intestine. Joints.
As with lupus, the incidence of scleroderma is higher in people of color. The disease typically affects individuals between the ages of 25 and 55 (slightly older than for lupus), and women are four-times more likely to have it than men. Children can develop scleroderma, though only about 2% will have symptoms before the age of 10.
The most popular approach to controlling the inflammatory phase of scleroderma is the use of immunosuppressive therapy. The rationale is that an autoimmune process is causing the inflammation and the downstream result is tissue damage and fibrosis. In this model, the fibrosis is an “innocent bystander” that is driven by the cytokines ...
- Many medications are thought to directly or indirectly affect inflammation. In scleroderma, there are two major types of inflammation that are rela...
- The vascular disease in scleroderma is widespread and affects medium and small arteries. It is manifest clinically as Raynaud’s phenomenon in the s...
May 25, 2022 · Symptoms. Early indications of mixed connective tissue disease can include: General feeling of being unwell. This can include increased fatigue and a mild fever. Cold and numb fingers or toes (Raynaud's phenomenon). In response to cold or stress, your fingers or toes might turn white and then purplish blue.
Feb 8, 2023 · Depending on your symptoms, treatment can also include: ... Lupus, rheumatoid arthritis, and scleroderma are all types of collagen vascular disease. READ MORE. Necrotizing Vasculitis.
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Treatment works best when started early. If the diagnosis is scleroderma, treatment is most effective when started shortly after the disease has begun. At that time, physical and occupational therapy can help you keep your ability to straighten and bend your joints and maintain your daily life. Started early, treatments like phototherapy (light ...