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  1. SCORE risk ≥10%, documented cardiovascular disease, diabetes with end-organ damage or at least 1 major risk factor, severe chronic kidney disease: High risk: SCORE risk 5%–9%, a very high single risk factor, most others with diabetes, moderate chronic kidney disease: Moderate risk: SCORE risk 1%–4%, many middle-aged persons: Low risk ...

    • Ian M Graham, Emanuele Di Angelantonio, Frank Visseren, Dirk De Bacquer, Brian A Ference, Adam Timmi...
    • 2021
  2. Jul 20, 2022 · Systematic Coronary Risk Evaluation (SCORE) SCORE (Systematic Coronary Risk Evaluation) ( Figure 1 ) predicts the 10-year risk of cardiovascular mortality and was developed from 12 European cohort studies (n = 205,178) with 7934 cardiovascular deaths [ 6 , 7 ].

    • 10.3390/jpm12071180
    • 2022/07
    • J Pers Med. 2022 Jul; 12(7): 1180.
  3. Nov 28, 2023 · The new Systematic Coronary Risk Evaluation (SCORE2 and SCORE2-OP) estimates the risk of arterial occlusive events in chronic myeloid leukemia patients treated with nilotinib or ponatinib.

    • 10.1007/s00277-023-05556-0
    • 2024
    • Ann Hematol. 2024; 103(2): 427-436.
    • Key Features of CVD Risk Calculators
    • CVD Risk Calculators in Asia and Brunei Darussalam
    • Recommendations

    Development and validation

    The WHO/ISH risk prediction charts seem the only option available for the populations for which prospective studies are not available . The WHO CVD Risk Chart Working Group updated the WHO CVD risk charts in 2019 based on newly validated risk prediction models using Cox proportional hazards models to estimate CVD risk in 21 Global Burden of Disease (GBD) regions . It utilised data from 85 prospective cohorts based on the Emerging Risk Factors Collaboration (ERFC). The charts are recal...

    Variables

    It is highlighted in Table 4 that the WHO/ISH CVD risk chart variables were gender, age, systolic blood pressure (SBP), presence or absence of diabetes, total cholesterol level (mmol/l), and smoking status . The QRISK® risk score incorporates more variables including ethnicity, relevant family history (angina or heart attack in a first-degree relative younger than 60 years old), cholesterol/HDL ratio, body mass index, hypertensive medication, rheumatoid arthritis, chronic kidney disease an...

    Predictive accuracy

    Studies showed that the WHO/ISH risk prediction model identifies most people with low CVD risk, for instance, 97% (95% CI 96.4, 97.7) for Cambodia, 89.6% (95%CI 86.8, 92.2) for Mongolia and 94.4% (95%CI 91, 97.8) for Malaysia . The prevalence of low CVD risk was 89.3% in Jamaica and 89.7% in Cuba . Another study reported that the prevalence of CVD risk factors was high, but it did not translate into high CVD risk categorisation . In addition, the prevalence of high total CVD...

    The existing CVD risk-assessment tools are not universal due to genetic differences, cultures, lifestyle habits, and social and behavioural characteristics . The Asia Pacific Cohort Studies Collaboration showed higher systolic blood pressure, total cholesterol, and CVD events in Framingham than in the Asian cohorts. Smoking is higher in the Asian c...

    The countries that need to develop national CVD risk calculators or plan to use one of the currently available CVD risk assessment tools should consider the key features that could affect the validity and accuracy of the calculator in determining the usability and benefits of the tool in its respective health care settings. Also, there is a need to...

  4. Jul 14, 2017 · The objective of this study is to assess the effect of total cardiovascular risk estimation using the SCORE in preventing serious cardiovascular events in European adults without prior CVD. Methods and results: Data sources: eight bibliographical databases (2003 – August 2015), other internet sources and reference lists of articles were checked.

    • Tomasz Tomasik, Janusz Krzysztoń, Katarzyna Dubas-Jakóbczyk, Violetta Kijowska, Adam Windak
    • 2017
  5. Abstract. Objectives: The SCORE model predicts the ten-year risk of cardiovascular mortality but it is still unknown whether applying the SCORE in clinical practice subsequently improves cardiovascular disease (CVD) outcomes. The objective of this study is to assess the effect of total cardiovascular risk estimation using the SCORE in ...

  6. Apr 9, 2020 · European guidelines recommend the use of the Systematic COronary Risk Evaluation (SCORE) to assess 10-year risk of fatal cardiovascular events in people aged 40 to 65. The SCORE Older Persons (SCORE OP, 5-year and 10-year versions) was recently developed for people aged 65 or older.

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