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  1. Jul 8, 2019 · As a consequence of this local, intracrine, system, immune responses may vary according to the availability of 25-OHD3, and vitamin D deficiency has been linked to various autoimmune disorders including rheumatoid arthritis (RA).

    • Fig. 1

      Role of vitamin D in the immune system. Schematic...

  2. Oct 30, 2020 · We summarize the research status of vitamin D supplementation in patients with rheumatoid arthritis and provide data to support future clinical treatment and trials of rheumatoid arthritis.

    • Yuanyuan Guan, Yang Hao, Yun Guan, Huaien Bu, Hongwu Wang
    • 10.3389/fmed.2020.596007
    • 2020
    • Front Med (Lausanne). 2020; 7: 596007.
  3. People also ask

    • Overview
    • How can RA affect the toes?
    • Symptoms
    • Diagnosis
    • Treatments
    • When to see a doctor
    • Summary

    Rheumatoid arthritis (RA) is an autoimmune disease that causes painful swelling in various joints of the body, including the toes and the other joints of the feet. There is no cure for RA, but treatments can help prevent and slow damage.

    RA can affect any joint in the body, but about 20% of people with the disease first notice symptoms in their toes, feet, and ankles.

    RA is an autoimmune, inflammatory disease, and its symptoms result from the immune system overreacting to and mistakenly attacking parts of the body.

    When a person has RA, the overreactive immune system attacks tissues such as ligaments and bones. It can also damage blood vessels, nerves, and organs, including the lungs and heart.

    By damaging bones and soft tissues, this chronic disease causes pain, swelling, and decreased range of motion in the joints. Although it can affect any of the joints in the body, it most often affects smaller joints, such as those of the feet.

    RA is a chronic disease, meaning that it is a long lasting condition with no cure. It is the most common form of autoimmune arthritis, affecting more than 1.3 million people in the United States.

    RA causes an inflammatory reaction in the synovium, the lining that lubricates and protects the joints. In healthy joints, the synovium facilitates movement. In an RA-affected joint, the lining swells, damaging the joint and the tissues that support it, such as ligaments. When the ligaments and other supporting tissues become damaged, this can cause joint deformities.

    In the toes and feet, RA can cause:

    •Hammer toe: This deformity of the second, third, or fourth toe causes the toe to bend at the middle joint.

    •Claw toe: In those with this condition, the toes bend into a claw-like position.

    •Bursitis: Bursitis is the term for the inflammation of the fluid filled sacs of the joints.

    •Bunions: A bunion is a painful, bony lump or bump on the big toe that occurs when the bones move out of place.

    Aside from the foot conditions above, a person with RA may notice other symptoms that include:

    •aching pain in more than one joint

    •long lasting morning stiffness

    •joint swelling

    A person with RA will experience the same symptoms in the joints on both sides of their body. Therefore, anyone with RA who experiences foot-related symptoms will experience the symptoms in both feet. According to the American Academy of Orthopaedic Surgeons, RA will affect the same joints in each foot.

    RA can also cause systemic symptoms, including:

    The signs and symptoms of RA can mimic the symptoms of other conditions, making the disease difficult to diagnose. Due to this, a person will often need to see a specialist called a rheumatologist for a diagnosis.

    At the appointment, the rheumatologist will take a detailed history, documenting the timeline of the person’s symptoms, and perform a physical exam, focusing on all joints. If the symptoms primarily affect the feet, the rheumatologist will examine the individual’s ankles and feet to check for the following:

    •calluses, corns, and other skin conditions

    •deformities such as hammer toe and claw toe

    •bunions

    •tenderness to touch

    There is no cure for RA, so treatments center around controlling the symptoms and alleviating joint pain and swelling. Finding the right treatment can often take a bit of trial and error. There is no single treatment that works for all people with RA.

    The severity of a person’s condition will determine what treatments the doctor recommends. When RA affects the toes, the suggested treatments may include lifestyle adjustments, medication, and surgery.

    Making appropriate lifestyle adjustments is often one of the first steps toward managing pain and other RA symptoms. Options that may provide relief include:

    •resting the affected joints by taking a break from activities that place stress on the toes and feet

    •wrapping ice packs in material and applying them to swollen or tender areas

    •using braces

    Anyone with any symptoms of RA should see a doctor within 6 months of the onset of symptoms. Early diagnosis and treatment can slow the progression of RA.

    Once a person has received a diagnosis of RA, they should see a doctor regularly to monitor their condition. Aside from regular checkups, a person with RA should also speak with a doctor if they have any new or worsening symptoms.

    Rheumatoid arthritis is a chronic autoimmune disease that damages the joints in a person’s body. It often affects the small joints in the feet, including the toe joints, initially.

    The condition can cause pain, swelling, and joint deformity.

  4. Sep 17, 2019 · If you have arthritis in your toes, it’s important to understand the type of arthritis that might be causing it, because each type of arthritis has specific medications and treatments. Here are some of the more common types of arthritis that strike in toes.

  5. May 16, 2024 · Stiffness and loss of function: Arthritis can cause an inability to bend the big toe upward, which can be painful and make it difficult to walk. The toe can become permanently bent downward and...

  6. 1 day ago · Arthritis in the toes can lead to pain, swelling, and stiffness making it difficult to stay on your feet. Causes may include osteoarthritis, rheumatoid arthritis, injury, or gout. Arthritis in the toes may be treated with heat and cold therapy, NSAIDs, injections, or special footwear.

  7. 1) Dietary intake. Few foods contain vitamin D naturally, such as salmon, egg yolk, shrimps, etc. While in some, vitamin D is added to make them fortified with the nutrients. Such include milk, cereal, yogurt, and orange juice. You can obtain both vitamin D2 and D3 from food sources. 2) Sun exposure.