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  1. The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.

    • Table 1

      Given the wide heterogeneity of phenotypes and of the...

    • Mcmdm-1Vwd

      Introduction. von Willebrand factor (VWF) is a multimeric...

  2. Jun 7, 2022 · Von Willebrand disease (VWD), first described by Dr. Erik von Willebrand, is the most common autosomal inherited bleeding disorder. It is caused by deficiency or dysfunction of von Willebrand factor (VWF), a plasma protein that mediates the initial adhesion of platelets at sites of vascular injury, and binds and stabilizes blood clotting factor ...

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  4. Nov 30, 2009 · Pregnancy and delivery are considered situations predisposing to a high risk of bleeding in women with von Willebrand’s disease (VWD). 1, 2 While patients with mild deficiency usually show a spontaneous complete correction of basal low factor VIII (FVIII) and von Willebrand factor (VWF) levels during pregnancy, patients with dysfunctional (type ...

    • Giancarlo Castaman, Alberto Tosetto, Francesco Rodeghiero
    • 10.3324/haematol.2009.011239
    • 2010
    • Haematologica. 2010 Jun; 95(6): 963-969.
  5. Now known as von Willebrand disease In 1926, Erik von Willebrand first de- (VWD), this disorder is caused by either scribed a familial bleeding disorder in a quantitative or qualitative defect in von which symptoms were more severe in Willebrand factor (VWF). The preva-children and young women.

  6. May 15, 2024 · With proper care, women with von Willebrand disease (VWD) can have a successful pregnancy and deliver a healthy child. Close monitoring throughout pregnancy is important for women with VWD. Women with VWD are at risk for serious bleeding after delivery.

  7. Oct 26, 2021 · A Book: Mayo Clinic Family Health Book, 5th Edition. Newsletter: Mayo Clinic Health Letter — Digital Edition. Symptoms. Many people with von Willebrand disease don't know it because the signs are mild or absent. The most common sign of the condition is abnormal bleeding. There are three main types of the disease.

  8. May 20, 2019 · The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.

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