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Mar 31, 2023 · Von Willebrand disease (vWD) is a common, inherited, genetically and clinically heterogeneous hemorrhagic disorder caused by a deficiency or dysfunction of the protein termed von Willebrand...
Mar 31, 2023 · How does pregnancy affect the levels of von Willebrand factor (vWF) in patients with non-type 3 von Willebrand disease (vWD)? What are the possible complications in pregnant patients with...
Jun 23, 2021 · Although referred to as a single disease, von Willebrand disease (VWD) is in fact a family of bleeding disorders caused by an abnormality of the von Willebrand factor (VWF). von Willebrand...
Sep 25, 2017 · Causes include subinvolution of the placental site, retained products of conception, infection, and inherited coagulation defects (eg, factor deficiency such as von Willebrand).
The course and outcome of pregnancy in women with different types of von Willebrand disease (3 type I, 1 subtype IIA, and 1 subtype IIB) are described. In all patients, factor VIII increased and reached normal levels before delivery, whereas the bleeding time remained prolonged; in subtypes IIA and IIB the abnormal multimeric structure of von ...
Jan 20, 2022 · von Willebrand disease is the most common inherited bleeding abnormality, with a prevalence rate of 0.8-1.3%. This disorder is secondary to a decrease or defect in the von Willebrand portion...
High levels of high-molecular weight von Willebrand factor in maternal serum reflect the virtual absence of the metalloprotease ADAMTS13 enzyme which is required to control the level of the factor.
