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  1. Prothrombin Gene Mutation. Who treats bleeding and clotting disorders at Children’s? What is Von Willebrand disease? Von Willebrand disease (vWD) is a lifelong bleeding disorder caused by a defect or deficiency of a blood-clotting protein called von Willebrand factor.

  2. Key Points. Von Willebrand disease (VWD) is a blood disorder in which the blood does not clot properly. VWD is the most common bleeding disorder. Signs of VWD include nosebleeds, easy bruising, heavy menstrual bleeding, and longer than normal bleeding after injury, surgery, dental work, or childbirth.

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    • What Causes VWD?
    • What Are The Symptoms of VWD?
    • How Is VWD Diagnosed?
    • How Is VWD Treated?
    • What Are Possible Complications of VWD?
    • How Is VWD Managed?
    • When Should I Call My Child's Healthcare Provider?
    • Key Points About VWD
    • Next Steps

    VWD is almost always inherited. This means it is passed from parents to children. People with the disorder may have low levels of a blood protein called von Willebrand factor. It helps the platelets in blood stick together to stop bleeding. Sometimes von Willebrand factor is in the blood, but not working well. VWD may also cause problems with anoth...

    The symptoms of VWD vary, depending on the type. Type 1 and type 2 generally have: 1. Frequent or long-lasting nosebleeds 2. Large bruises from minor injuries 3. Blood in the stool or urine 4. Heavy bleeding from cuts, dental work, or surgery 5. Heavy menstrual bleeding Children with type 3 VWD also have these symptoms. But they may also have sever...

    Your child's healthcare provider will check your child for signs of bruising and bleeding. He or she will ask many questions about your child's symptoms and about your family history. Samples of your child's blood will be taken to check: 1. Complete blood count (CBC).A complete blood count checks the red and white blood cells, blood clotting cells ...

    Long-term medicine is usually not needed. If your child has repeated bleeding inside his or her body (for example, in the joints), long-term medicine may be needed. Medicines may be used to stop bleeding, should it occur. They may also be used to prevent bleeding with planned surgery or dental work. One medicine is desmopressin. It is a hormone tha...

    Possible complications of VWD include: 1. Severe bleeding with pain and swelling 2. Anemia or low levels of red blood cells or hemoglobin, the part of the blood that carries oxygen 3. Heavy menstrual periods 4. Problems with pregnancy

    You can take these steps to reduce your child's risk for bleeding: 1. Not giving your child blood-thinning medicines such as aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen. 2. Discouraging your child from taking part in sports like football, hockey, and weightlifting. Injuries may lead to bleeding. 3. Having your child wea...

    Call your child's healthcare provider if your child has bleeding that you cannot stop. If your child has pain or swelling, you should call your child's healthcare provider right away.

    VWD is an inherited disorder that affects the blood's ability to clot.
    Most people with VWD have a mild form.
    VWD is diagnosed with blood tests.
    Medicines may be used to stop bleeding or to prevent bleeding with planned procedures.

    Tips to help you get the most from a visit to your child’s healthcare provider: 1. Know the reason for the visit and what you want to happen. 2. Before your visit, write down questions you want answered. 3. At the visit, write down the name of a new diagnosis, and any new medicines, treatments, or tests. Also write down any new instructions your pr...

  4. Von Willebrand disease is a bleeding disorder that affects the blood’s ability to clot. A person with von Willebrand disease may have increased bruising, prolonged nosebleeds, mouth bleeds, heavy periods or heavy bleeding that’s hard to stop after an injury or procedure.

  5. What is von Willebrand disease? Von Willebrand disease (VWD) is an inherited bleeding disorder caused by an abnormal blood-clotting protein called von Willebrand factor (VWF). The VWF is important for the body to create the first steps of a blood clot to stop bleeding with injury and surgery.

  6. Oct 26, 2021 · If you have the gene for von Willebrand disease, you have a 50% chance of transmitting this gene to your children. The most severe form of the condition is "autosomal recessive," which means both of your parents have to pass a mutated gene to you.

  7. May 15, 2024 · A combination of blood tests is needed to diagnose von Willebrand disease (VWD). The following screening tests are done first to show if the blood is clotting properly. These tests may suggest a possible bleeding disorder, but more tests are needed to tell the type of bleeding disorder present. Screening tests are often normal in VWD, and more ...

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  2. Visit our site to view resources for adult patients with von Willebrand disease.

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