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  1. The diagnosis was proliferative disorder of CD3 + granular lymphocytes, with associated pancytopenia. Because the blast cells were morphologically similar to myeloblasts and immunohisto- chemistry was required to confirm the diagnosis, T-cell lymphoproliferative disease should be considered in dogs with pancytopenia presenting with similar ...

    • Marjorie J. Williams, David Gardiner, Davis Seelig, Christine S. Olver
    • Veterinary Clinical Pathology
    • 2008
    • English (US)
  2. Hematologic recovery and patient survival time varied with the cause of pancytopenia; therefore, a specific diagnosis was essential for establishing prognosis. Differentiation among causes of pancytopenia requires a systemic approach that includes elimination of infectious and drug-induced causes, and examination of bone marrow aspiration and ...

    • Douglas J. Weiss, Oral A. Evanson, Jane E Sykes
    • 1999
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  4. Feb 25, 2020 · Idiopathic aplastic pancytopenia in dogs generally carries a poor prognosis with a reported 21‐day mortality rate of 80%.1 The high mortality rate reported in dogs likely reflects poor response to immunosuppressive treatment, similar to the poor response seen when immunosuppressive treatment is used alone in human patients. The decision to ...

    • Darren Kelly, Valerie Lamb, Florence Juvet
    • 2020
  5. Conclusions: Aplastic pancytopenia is diagnosed infrequently and idiopathic aplastic pancytopenia may account for up to 67% or more of canine cases. Although the prognosis is guarded, some dogs with aplastic pancytopenia recover.

    • Jennifer L. Brazzell, Douglas J. Weiss
    • 2006
  6. Nov 19, 2008 · The diagnosis was proliferative disorder of CD3 + granular lymphocytes, with associated pancytopenia. Because the blast cells were morphologically similar to myeloblasts and immunohistochemistry was required to confirm the diagnosis, T-cell lymphoproliferative disease should be considered in dogs with pancytopenia presenting with similar ...

    • Marjorie J. Williams, David Gardiner, Davis Seelig, Christine S. Olver
    • 2008
  7. Abstract: A 4-year-old male, castrated, mixed-breed dog was presented to the Colorado State University Veterinary Teaching Hospital with a 1-week history of polyuria, polydipsia, lethargy, fever, in...

  8. One dog remained severely pancytopenic 4 weeks post-operatively and received oral lithium treatment. Improvements in all blood cell lines were observed within the 4 weeks and resolution of pancytopenia within 6 weeks. Historically, the prognosis for dogs with bone marrow suppression secondary to Sertoli cell tumours was guarded to poor.

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