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  1. Abstract. After failed attempts at producing bacteria-based vaccines, the discovery of a viral agent causing yellow fever and its isolation in monkeys opened new avenues of research. Subsequent advances were the attenuation of the virus in mice and later in tissue culture; the creation of the seed lot system to avoid spontaneous mutations; the ...

    • Frierson Jg
    • 2010
  2. Scientists who conducted this trial found that some of the vaccine’s recipients developed complications such as serum sickness, rash, and jaundice; these complications were attributed to reaction to anti–yellow fever serum. 7 George Marshall Findlay and his colleagues from the Wellcome Foundation’s virology laboratory in London, who also ...

    • Ilana Löwy
    • 2021
  3. Sep 1, 2022 · Yellow fever is a zoonotic arbovirosis, the agent of which is transmitted by mosquitoes. In humans, this virus can cause hemorrhagic hepato-nephritis, while mild or inapparent infections are common. The catastrophic epidemics that occurred, mainly in the 18 th and the 19 th centuries, in Latin America and the United States as well as in the ...

  4. Sep 1, 2021 · The disease yellow fever (YF) is prevented by a live-attenuated vaccine, termed 17D, which has been in use since the 1930s. One dose of the vaccine is thought to give lifelong (35+ years) protective immunity, and neutralizing antibodies are the correlate of protection. Despite being a vaccine-preventable disease, YF remains a major public ...

    • Clairissa A Hansen, Alan D T Barrett
    • 10.3390/ph14090891
    • 2021
    • 2021/09
  5. May 15, 2024 · Yellow fever vaccine is recommended for persons aged ≥9 months traveling to or living in areas of South America and Africa with a risk of yellow fever. Because serious adverse events occur, clinicians should vaccinate only persons at risk for exposure to yellow fever virus or require proof of vaccination for country entry.

  6. In the summer of 1693, a strange disease spread through Boston. Victims suffered from jaundice, high fever and black vomit. For more than two hundred years, yellow fever — as the disease became ...

  7. Download (PPT) The 1951 Nobel Prize for medicine or physiology was awarded to South African physician and microbiologist Max Theiler for his discoveries concerning yellow fever and its treatment. His work not only resulted in the development of a vaccine against yellow fever but also showed how vaccines could be developed against other diseases.

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