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  1. Abstract. After failed attempts at producing bacteria-based vaccines, the discovery of a viral agent causing yellow fever and its isolation in monkeys opened new avenues of research. Subsequent advances were the attenuation of the virus in mice and later in tissue culture; the creation of the seed lot system to avoid spontaneous mutations; the ...

    • Frierson Jg
    • 2010
  2. Sep 1, 2022 · Yellow fever is a zoonotic arbovirosis, the agent of which is transmitted by mosquitoes. In humans, this virus can cause hemorrhagic hepato-nephritis, while mild or inapparent infections are common. The catastrophic epidemics that occurred, mainly in the 18 th and the 19 th centuries, in Latin America and the United States as well as in the ...

  3. The yellow fever vaccine produced at Fiocruz (previously Oswaldo Cruz Institute) is still the 17D attenuated strain, and the vaccine department proudly preserves the first vials of the vaccine from 1937. In 2021, this vaccine is manufactured at the ultra-modern glass-and-steel building of Bio-Manguinhos, but this is a relatively new development.

    • Ilana Löwy
    • 2021
  4. Download (PPT) The 1951 Nobel Prize for medicine or physiology was awarded to South African physician and microbiologist Max Theiler for his discoveries concerning yellow fever and its treatment. His work not only resulted in the development of a vaccine against yellow fever but also showed how vaccines could be developed against other diseases.

    • Marc A. Shampo, Robert A. Kyle
    • 2003
  5. May 15, 2024 · Yellow fever vaccine is recommended for persons aged ≥9 months traveling to or living in areas of South America and Africa with a risk of yellow fever. Because serious adverse events occur, clinicians should vaccinate only persons at risk for exposure to yellow fever virus or require proof of vaccination for country entry.

  6. Yellow fever vaccine is a live vaccine containing weakened, live yellow fever virus. It is given as a single shot. One dose provides lifelong protection for most people. Yellow fever vaccine is recommended for: People 9 months through 59 years of age who are traveling to or living in areas at risk for yellow fever virus activity, or traveling ...

  7. Nov 8, 2023 · Yellow fever is a viral disease that is transmitted to humans by the bites of infected mosquitoes. It is prone to epidemics and is preventable with a vaccine. These day-biting mosquitoes breed around houses (domestic), in forests or jungles (wild), or in both habitats (semi-domestic).