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  1. Metabolic acidosis is a serious electrolyte disorder characterized by an imbalance in the body's acid-base balance. Metabolic acidosis has three main root causes: increased acid production, loss of bicarbonate, and a reduced ability of the kidneys to excrete excess acids.

  2. Nov 23, 2016 · Predialysis serum bicarbonate Acid generation rate, including dietary protein intake Interdialytic weight gain Time since last dialysis (i.e., long versus short interval) Phosphorus binder use Postdialysis serum bicarbonate a: Postdialysis serum bicarbonate Dialysate bicarbonate concentration

    • Matthew K. Abramowitz
    • 10.1681/ASN.2016070780
    • 2017
    • J Am Soc Nephrol. 2017 Mar; 28(3): 726-734.
  3. Sep 9, 2021 · Multiple-day protocols of sodium bicarbonate supplementation can be effective in improving exercise performance. The duration of these protocols is generally between 3 and 7 days before the exercise test, and a total sodium bicarbonate dose of 0.4 or 0.5 g/kg per day produces ergogenic effects.

    • Jozo Grgic, Zeljko Pedisic, Bryan Saunders, Guilherme G. Artioli, Brad J. Schoenfeld, Michael J. McK...
    • 2021
  4. Sep 25, 2021 · May Improve Athletic Performance . Research has shown that sodium bicarbonate may help create a performance-enhancing effect. A review from the Journal of Sports Science & Medicine found that supplemental sodium bicarbonate can reduce acidosis during exercise —a condition in which you have too much acid in the body fluids—allowing for improved athletic abilities.

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  6. Jun 7, 2013 · PMCID: PMC3682661. NIHMSID: NIHMS465736. PMID: 23570729. Use of sodium bicarbonate to promote weight gain, maintain body temperature, normalize renal functions and prevent mortality in rodents receiving the chemotherapeutic agent cisplatin. Josée Guindon 1,2 and Andrea G. Hohmann 1,2.

    • Josée Guindon, Andrea G. Hohmann, Andrea G. Hohmann
    • 10.1016/j.neulet.2013.03.033
    • 2013
    • 2013/06/06
  7. Aug 15, 2019 · The BICAR-ICU study compared intravenous administration of 4.2% sodium bicarbonate (q.s. pH > 7.30) with a control arm without infusion of bicarbonate in patients with severe metabolic acidosis (pH ≤ 7.20, bicarbonate < 20 mmol/L and PaCO 2 ≤ 45 mmHg) and a SOFA score ≥ 4 or arterial blood lactate ≥ 2 mmol/L. This randomized, controlled ...

  8. Sep 2, 2017 · Sodium Bicarbonate (NaHCO3): Properties, Structure, and Uses | Chemical Formula: NaHCO3Molecular Weight/Molar Mass: 84.0066 g/molDensity: Solid Form - 2.20 g/cm3; Powder Form - 1.1 – 1.3 g/cm3Boiling Point: 851 °CMelting Point: 50 °C.

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