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  1. Jul 31, 2023 · Mueller SM, et al. Multiday acute sodium bicarbonate intake improves endurance capacity and reduces acidosis in men. J Int Soc Sports Nutr. 2013 Mar 26;10(1):16. About Nick English

    • Effects of Sodium Bicarbonate Supplementation on Muscular Endurance
    • Effects of Sodium Bicarbonate Supplementation on Muscular Strength
    • Side-Effects Associated with Sodium Bicarbonate Supplementation
    • Methodological Quality
    • Strengths and Limitations
    • Recommendations For Future Research
    • Practical Implications

    The favorable effect of sodium bicarbonate supplementation on muscular endurance can be explained by the suggested physiological mechanisms of this supplement. Specifically, sodium bicarbonate elicits its performance-enhancing effect on exercise tasks that produce a substantial increase in H+ [6, 22, 52]. H+ accumulation is theorized to inhibit act...

    The pooled SMD for the effect of sodium bicarbonate on muscular strength was very close to zero, with both the upper and lower limit of CI within the range of trivial effects. This suggests that, even if an effect exists (regardless of whether it is positive or negative), it is most likely practically negligible. From a physiological perspective, t...

    Potential gastrointestinal side-effects are important to consider in relation to sodium bicarbonate supplementation. The buildup of CO2 in the gut, as a result of supplementation with sodium bicarbonate, may cause bloating, nausea, vomiting, and abdominal pain [55, 56]. Some of these side-effects were reported in the included studies (Table 1), alt...

    Most studies included in this review used a double-blind study design, which is identified as the “gold standard” study design in this line of research . However, none of the included studies explored the effectiveness of the blinding by asking the participants to indicate which trial was the sodium bicarbonate and which was the placebo. Given that...

    The key strengths of this review are: (a) the use of a broad search syntax; (b) the search for published literature in five bibliographic databases; (c) the comprehensive forward and backward citation tracking; and (d) following a strict protocol for systematic reviews. The main limitation of this review is that, out of the total of 192 participant...

    The findings presented in this review highlight the potential of sodium bicarbonate to acutely enhance muscular endurance. Given these acute benefits, future long-term studies are needed to explore if chronic supplementation also enhances hallmark adaptations to resistance training, such as hypertrophy and strength. Some studies using long-term sod...

    Individuals interested in acute enhancement of muscular endurance during resistance exercise may consider supplementing with sodium bicarbonate. Practically speaking, sodium bicarbonate supplementation may lead to a small increase in the number of performed repetitions at a given load, isokinetic total work, or the time to maintain an isometric act...

    • Jozo Grgic, Ramon F. Rodriguez, Alessandro Garofolini, Bryan Saunders, David J. Bishop, David J. Bis...
    • 2020
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  3. Nov 18, 2021 · Based on meta-analyses of moderate to high quality, it can be concluded that sodium bicarbonate supplementation acutely enhances peak anaerobic power, anaerobic capacity, performance in endurance events lasting ∼45 s to 8 min, muscle endurance, 2000-m rowing performance, and high-intensity intermittent running.

    • Jozo Grgic, Ivana Grgic, Juan Del Coso, Brad J Schoenfeld, Zeljko Pedisic
    • 10.1186/s12970-021-00469-7
    • 2021
    • J Int Soc Sports Nutr. 2021; 18: 71.
  4. Apr 1, 2022 · Review. Effects of sodium bicarbonate supplementation on exercise performance: an umbrella review. Jozo Grgic. , Ivana Grgic. , Juan Del Coso. , Brad J. Schoenfeld. & Zeljko Pedisic. Article: 71 | Published online: 01 Apr 2022. Cite this article. https://doi.org/10.1186/s12970-021-00469-7. In this article. Full Article. Figures & data. References.

  5. Sep 9, 2021 · Multiple-day protocols of sodium bicarbonate supplementation can be effective in improving exercise performance. The duration of these protocols is generally between 3 and 7 days before the exercise test, and a total sodium bicarbonate dose of 0.4 or 0.5 g/kg per day produces ergogenic effects.

    • Jozo Grgic, Zeljko Pedisic, Bryan Saunders, Guilherme G. Artioli, Brad J. Schoenfeld, Michael J. McK...
    • 2021
  6. Apr 1, 2022 · Review. Effect of sodium bicarbonate contribution on energy metabolism during exercise: a systematic review and meta-analysis. Jorge Lorenzo Calvo. , Huanteng Xu. , Daniel Mon-López. , Helios Pareja-Galeano. & Sergio Lorenzo Jiménez. Article: 11 | Published online: 01 Apr 2022. Cite this article. https://doi.org/10.1186/s12970-021-00410-y.

  7. Jul 25, 2020 · Results indicated that sodium bicarbonate supplementation enhanced muscular endurance, whether the task relied on small or large muscle groups. However, strength was not significantly improved, whether the task was completed in a rested or fatigued state.

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