Search results
Addition to buffering, sodium bicarbonate provides some nutritional benefit, while rarely displaying any cell toxicity. Formulated as 75g/L of water, excellent for supplementing dry powder medium during reconstitution.
- Gibco&Trade
- Sustainable packaging
- 0.075
- Sodium Bicarbonate
In addition to buffering, sodium bicarbonate provides some nutritional benefit, while rarely displaying any cell toxicity. Formulated as 75 g per liter of water, Gibco™ Sodium Bicarbonate, 7.5% Solution is perfect for supplementing dry powder medium during reconstitution.
Addition to buffering, sodium bicarbonate provides some nutritional benefit, while rarely displaying any cell toxicity. Formulated as 75g/L of water, excellent for supplementing dry powder medium during reconstitution.
Nov 12, 2020 · Remifentanil reconstituted with 8.4% sodium bicarbonate solution in isolation had an average pH of 8.7 over 24 h for all concentrations examined, and resulted in the concentration of remifentanil decreasing rapidly.
- Emily Henkel, Rebecca Vella, Kieran Behan, David Austin, Peter Kruger, Andrew Fenning
- 10.1186/s12871-020-01194-5
- 2020
- BMC Anesthesiol. 2020; 20: 283.
People also ask
What is sodium bicarbonate used for?
What is the concentration of remifentanil reconstituted with sodium bicarbonate?
Does sodium bicarbonate affect remifentanil degradation?
What is the final sodium bicarbonate concentration used in the media?
- Important Information
- Available Preparations
- Infusion Fluids
- Methods of Intravenous Administration
- Dose in Adults
- Monitoring
- Further Information
- References
Any reference to mmolrefers to both sodium and bicarbonate (as they are equimolar)Equivalencies: 1mmol is equivalent to 1mEq bicarbonateExcept in emergencies, the 8.4% infusion MUSTbe given via a central lineSee monitoring requirementsoverleafSodium bicarbonate 1.26% 75mmol (mEq) per 500ml infusion (Braun polyfusor) Sodium bicarbonate 8.4% 100mmol (mEq) per 100ml infusion (Braun) Sodium bicarbonate 8.4% in 10mmol (mEq) per 10ml (Martindale) (unlicensed)
Not required (product ready for use as is)If required the 8.4% infusion may be further diluted with Glucose 5% - see under further informationBolus intravenous injection 1. In emergency situations can give (8.4%) as a bolus injection Intermittent intravenous infusion (administer using an electronically controlled infusion device) 1. Peripheral line - use 1.26%strength 2. Central line- use any strength up to 8.4% 3. See under 'Dose' below for more detail
Cardiac arrest 1. Routine use is not recommendedbut see specialist guidelines Metabolic acidosis 1. Seek specialist advice regarding dosage 2. Usually administered over 3 to 4 hours in an amount appropriate to body base deficit (ref 1) 3. If acid-base status not available: give 2 to 5mmol/kg, infused over 4 to 8 hours (ref 2) 4. Subsequent doses sh...
Monitor pH, serum bicarbonate, and arterial blood gases (ref 1)Frequent monitoring of serum electrolyte concentrations and acid-base status is essential during treatmentWatch for consequences of sodium loadMonitor for extravasationExcept in emergencies, Sodium bicarbonate 8.4% should be administered via a central venous catheteras it has an osmolarity of about 2000mOsm/L (ref 2)Hypertonic solution (greater than 1.4%) may cause venous irritation, and extravasation may lead to tissue necrosisAccidental intra-arterial administration of the 8.4% preparation may cause shock, or may lead to the loss of an extremityAdditions of other drugs should never be made to sodium bicarbonate infusions, particularly calcium and magnesium salts (ref 1)SPC 8.4% March 2018 1. Injectable medicines administration guide Medusa, downloaded 26th Feb 2019 2. Uptodate - accessed online 11th March 2019 3. EVIQ guidelines: Prevention and management of Tumour Lysis Syndrome 25th May 2018
Intravenous sodium bicarbonate, also known as sodium hydrogen carbonate, is a medication primarily used to treat severe metabolic acidosis. [2] . For this purpose it is generally only used when the pH is less than 7.1 and when the underlying cause is either diarrhea, vomiting, or the kidneys. [3] .
Ask a question. solution (7.5%), sterile-filtered, BioReagent, suitable for cell culture. Sign In to View Organizational & Contract Pricing. Synonym (s): aqueous sodium bicarbonate. CAS Number: 144-55-8. MDL number: MFCD00003528.
