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1. www.nejm.org › doi › fullTwo Phase 3 Trials of Gantenerumab in Early Alzheimer’s ...

   www.nejm.org › doi › full

   Nov 15, 2023 · Published November 15, 2023. N Engl J Med 2023;389: 1862 - 1876. DOI: 10.1056/NEJMoa2304430. VOL. 389 NO. 20. Abstract. Background. Monoclonal antibodies that target amyloid-beta (Aβ) have the...

2. jbiomedsci.biomedcentral.com › articles › 10Clinical trials of new drugs for Alzheimer disease: a 2020 ...

   jbiomedsci.biomedcentral.com › articles › 10

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   Oct 2, 2023 · Clinical trials focusing on new drugs for AD were documented in 2020, but subsequent developments have emerged since then. Notably, the US-FDA has approved Aducanumab and Lecanemab, both antibodies targeting amyloid, marking the end of a nearly two-decade period without new AD drugs.

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4. People also ask

   Could early drug trials stop Alzheimer's?

   • Many researchers agree that the best test of the hypothesis — and the best way to stop the disease in its tracks — is to give people these drugs early, without waiting for Alzheimer’s symptoms to set in first. According to Hardy, designers of even the earliest trials might have realized that they were recruiting too late in the disease.

   Could drugs prevent Alzheimer’s? These trials aim to find out - Nature

   www.nature.com/articles/d41586-022-00651-0

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   Can a drug treat mild Alzheimer's?

   • These drugs are of the same type as aducanumab, made by Biogen in Cambridge, Massachusetts, which was provisionally approved last year by the US Food and Drug Administration (FDA) for the treatment of mild Alzheimer’s, in large part owing to its ability to remove amyloid-β.

   Could drugs prevent Alzheimer’s? These trials aim to find out - Nature

   www.nature.com/articles/d41586-022-00651-0

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   How many clinical trials are there on Alzheimer's disease?

   • The National Institute on Aging (NIA) is currently supporting 508 active clinical trials on Alzheimer’s disease and related dementias (AD/ADRD). These trials reflect diverse drug and mechanistic targets, as well as diversity in the stages of AD/ADRD they address.

   NIA-Funded Active Alzheimer’s and Related Dementias Clinical Trials and

   www.nia.nih.gov/research/ongoing-AD-trials

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5. www.nia.nih.gov › research › ongoing-AD-trialsNIA-Funded Active Alzheimer’s and Related Dementias Clinical ...

   www.nia.nih.gov › research › ongoing-AD-trials

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   The National Institute on Aging (NIA) is currently supporting 508 active clinical trials on Alzheimer’s disease and related dementias (AD/ADRD). These trials reflect diverse drug and mechanistic targets, as well as diversity in the stages of AD/ADRD they address.

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6. www.mayoclinic.org › diseases-conditions › alzheimerAlzheimer's treatments: What's on the horizon? - Mayo Clinic

   www.mayoclinic.org › diseases-conditions › alzheimer

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   Feb 13, 2024 · In 2023, the U.S. Food and Drug Administration (FDA) approved lecanemab (Leqembi) for people with mild Alzheimer's disease and mild cognitive impairment due to Alzheimer's disease. A phase 3 clinical trial found that the medicine slowed cognitive decline in people with early Alzheimer's disease.

7. www.alzdiscovery.org › uploads › media2021 ALZHEIMER’S CLINICAL TRIALS REPORT

   www.alzdiscovery.org › uploads › media

   17 Drugs for Alzheimer’s Prevention in Clinical Trials. 18 A Look at the ADDF Clinical Trial Portfolio. 25 Our Methods. 08 The Clinical Trials Pipeline. 14 Phase 3 Clinical Trials. 20 ADDF-Funded Research Snapshots. 09 Clinical Trials by the Numbers. 16 Drugs for Behavioral Symptoms in Clinical Trials. 22 Alzheimer’s Research Pipeline.

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8. www.alz.org › alzheimers-dementia › researchClinical Trials for Alzheimer's & Dementia | Alzheimer's ...

   www.alz.org › alzheimers-dementia › research

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   Learn how Alzheimer’s disease affects the brain. Don't just hope for a cure. Help us find one. Clinical trials and research studies for Alzheimer's disease or other dementias – use Alzheimer's Association TrialMatch, a free online matching tool.

9. www.nature.com › articles › d41586/022/00651-0Could drugs prevent Alzheimer’s? These trials aim to find out

   www.nature.com › articles › d41586/022/00651-0

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   Mar 9, 2022 · 09 March 2022. Could drugs prevent Alzheimer’s? These trials aim to find out. Researchers are giving drugs to healthy people in hope of clearing away toxic proteins in the brain and...