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  1. Specifically, the Third International Consensus Definitions for Sepsis and Septic Shock (Balamuth 2022) stresses that sepsis is a function of 4 variables, namely: threat to life. organ dysfunction (using pSOFA score) dysregulated host response. presence of highly suspected or documented infection.

  2. Sep 29, 2022 · Neonatal sepsis refers to an infection involving bloodstream in newborn infants less than 28 days old. It continues to remain a leading cause of morbidity and mortality among infants, especially in middle and lower-income countries.

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29
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  4. abstract. Early-onset sepsis (EOS) is a serious and potentially fatal complication of birth. Assessing term and late-preterm newborn infants for risk of EOS is one of the most common clinical tasks conducted by pediatric providers.1.

  5. Mar 19, 2020 · Recently, in adults, the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) have defined sepsis as a life-threatening organ dysfunction caused by a dysregulated...

    • Eleanor J. Molloy, James L. Wynn, Joseph Bliss, Joyce M. Koenig, Fleur M. Keij, Matt McGovern, Helmu...
    • 2020
  6. Jul 6, 2016 · Definition of Sepsis. Adult and pediatric intensivists currently use generally accepted definitions for sepsis for goal-based therapeutic interventions.6, 7, 8, 9 These definitions are critical to facilitate epidemiologic studies, to accurately determine disease prevalence, to select patients for clinical trials, and ultimately to improve the ...

    • James L. Wynn, Hector R. Wong
    • 10.1016/B978-0-323-35214-7.00152-9
    • 2017
    • 2017
  7. Sepsis has a huge impact on global mortality and has been declared as a priority by the World Health organisation the WHO.1 Children have a high incidence of sepsis especially in the neonatal...

  8. Sepsis is a dysregulated host response to infection leading to life- threatening organ dysfunction.1 Although neonates are highly vulnerable to sepsis, incidence estimates for this age group are lacking from many countries.2 Recently, the Global Burden of Disease (GBD) Study 2016/2017 estimated 1.3 (95% CI 0.8 to 2.3) million annual incident cas...

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