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High serum levels of TNF and its receptors are associated with severity of DF. Our patient had a severe form of dengue and potentially fatal outcome. Inhibition of an essential inflammatory pathway may have contributed to a favorable progression. A study using a mouse model demonstrated that treatment with anti-TNF reduced mortality.
Feb 28, 2020 · Psoriasis is a chronic inflammatory disease involving multiple organ systems and affecting approximately 2% of the world's population. In this guideline, we focus the discussion on systemic, nonbiologic medications for the treatment of this disease. We provide detailed discussion of efficacy and safety for the most commonly used medications, including methotrexate, cyclosporine, and acitretin ...
- Alan Menter, Joel M. Gelfand, Cody Connor, April W. Armstrong, Kelly M. Cordoro, Dawn M.R. Davis, Bo...
- 2020
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Apr 18, 2023 · In the absence of targeted dengue therapeutics, good supportive care, with treatment for symptom management and fluid administration, is the cornerstone of clinical management of dengue (Fig. 1). WHO guidelines recommend acetaminophen or paracetamol for antipyretics, with a recommended dose of 10 mg/kg/dose.
- 10.1007/s40506-023-00263-w
- 2023
Jan 1, 2023 · On the contrary, in those asymptomatic SARS-CoV-2+ patients with high-need-to-treat psoriasis, as well as in psoriasis patients who have had a severe hospital course or the persistence of 1 or more symptoms of COVID-19, beyond the acute phase of the illness, the decision to restart treatment should be taken on a case-by-case basis [76,77].
- 10.5826/dpc.1301a16
- 2023/01
- What Is Psoriasis?
- What Is Drug-Induced Psoriasis?
- Who Gets Drug-Induced Psoriasis?
- What Causes Drug-Induced Psoriasis?
- What Are The Clinical Features of Drug-Induced Psoriasis?
- How Is Drug-Induced Psoriasis Diagnosed?
- How Is Drug-Induced Psoriasis Treated?
- What Is The Outcome For Drug-Induced Psoriasis?
Psoriasis is a common chronic skin condition characterised by symmetrically distributed, well-defined scaly plaques. The most common type of psoriasis is chronic plaque psoriasis, which often starts in early adult life.
In some people, psoriasis is drug-induced or drug-aggravated. 1. In drug-induced psoriasis, discontinuation of the offending drug leads to the clearance of psoriasis. It occurs in patients with no previous history of psoriasis. 2. In drug-aggravated psoriasis, the disease continues to develop even after the causative drughas been discontinued. It t...
As with psoriasis that is not induced by a drug, drug-induced psoriasis occurs more frequently in patients with a history of: 1. Obesity 2. Smoking 3. Diabetes 4. Hypertension 5. Dyslipidaemia (metabolic syndrome). Other risk factors for psoriasis include: 1. Race — psoriasis occurs in all races, but it is more common in Caucasians than in those of...
The most common drugs to induce or aggravate psoriasis are: 1. β-blockers (in 20% of patients with psoriasis, eg, propranolol, metoprolol, bisoprolol) 2. Lithium(in 50% of patients with psoriasis) and less often, other medications that are given to improve mood 3. Antimalarial drugs (eg, hydroxychloroquine, chloroquine, quinacrine) 4. Antibiotics (...
Drug-induced or drug-aggravated psoriasis may induce: 1. Localised plaque psoriasis, often affecting scalp, knees, elbows, buttocks and/or genitals 2. Generalisedplaque psoriasis, with scattered plaques on all parts of the body 3. Erythrodermawhen the entire skin surface is red and scaly. Acute generalised exanthematous pustulosis (AGEP) is a sever...
Diagnosis of drug-induced psoriasis can be challenging when patients are on multiple medications. The onset of psoriatic symptoms can be months or years after the drug has been started. Careful patient history is essential in any patient that presents with new-onset psoriasis and must include their current medications. The possibility of other trig...
The standard of care in the case of drug-induced psoriasis is to discontinue the offending drug. However, this is not always possible; for example, in a patient with severe depression that is well controlled by lithium where other options have been ineffective or contraindicated. Treatments for psoriasis include: 1. Emollients 2. Topical corticoste...
While some cases of drug-induced psoriasis can resolve within weeks of stopping the causative medicine, in other cases, it can take much longer to resolve or not resolve completely.
Jun 23, 2022 · Effective relief of psoriasis can be achieved through interventions for infectious factors such as antibiotics, tonsillectomy, and probiotics [9,10,11]. This not only further illustrates the important link between infection and psoriasis development, but also inspires the treatment of psoriasis.
Apr 24, 2023 · Doctors usually prescribe antibiotics like penicillin or erythromycin ( Erythrocin) to treat strep infections and ease symptoms. Since these infections play a role in guttate psoriasis, a...
