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1. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.

2. www.nature.com › articles › nrdp201655Dengue infection | Nature Reviews Disease Primers

   www.nature.com › articles › nrdp201655

   Aug 18, 2016 · Four main factors control dengue virus (DENV) disease response along a response continuum: immune status, virus strain, genetic status and age. Individuals at risk of a secondary infection are...

   • Author: Maria G. Guzman

3. www.nature.com › articles › nmicrobiol201750Viral pathogenesis: Dengue virus takes on cGAS | Nature ...

   www.nature.com › articles › nmicrobiol201750

   Mar 27, 2017 · In this issue of Nature Microbiology, infection by dengue virus (DENV), which has an RNA genome, is shown to induce mitochondrial DNA release into the cytosol, leading to cGAS activation. In...

   • Author: Michiel van Gent, Michaela U. Gack

   • Publish Year: 2017

4. journals.sagepub.com › doi › 10Dengue Virus: Molecular Biology and Recent Developments in ...

   journals.sagepub.com › doi › 10

   Nov 19, 2023 · According to the World Health Organization (WHO) dengue guideline, the spectrum of DENV infection can vary from undifferentiated febrile illness or asymptomatic infection to more serious manifestations, including dengue shock syndrome (DSS) and dengue hemorrhagic fever (DHF). Methodology.

5. People also ask

   What is the pathogenesis of dengue?

   • The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   Are there any controversies about the pathogenesis of dengue fever?

   • In this paper, six controversies in relation to the pathogenesis of dengue fever are analysed and, where possible, resolved. Rosen, L. The Emperor's New Clothes revisited, or reflections on the pathogenesis of dengue hemorrhagic fever.

   Dengue infection | Nature Reviews Disease Primers

   www.nature.com/articles/nrdp201655

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   What is a severe dengue & DHF/DSS?

   • As such, severe dengue and DHF/DSS occur most often in individuals with monotypic immunity during a second heterotypic DENV infection. Severe cases also occur (infrequently) in primary infections. By contrast, third and fourth DENV infections are typically mild or asymptomatic 54, 55.

   Dengue infection | Nature Reviews Disease Primers

   www.nature.com/articles/nrdp201655

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6. www.ncbi.nlm.nih.gov › pmc › articlesDengue Virus - PMC - National Center for Biotechnology ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Sep 20, 2019 · In this chapter we will discuss the evolution of virus and its vector, epidemiology of dengue, molecular and genomic structure of DENV, their pathogenesis, immune response of the host to the infection, laboratory diagnosis, management, and recent developments in dengue drug and vaccine development.

   • Author: Amudhan Murugesan, Mythreyee Manoharan
   • Published: 2020

   • DOI: 10.1016/B978-0-12-819400-3.00016-8

7. www.sciencedirect.com › science › articleMolecular mechanisms in the pathogenesis of dengue infections

   www.sciencedirect.com › science › article

   May 1, 2024 · Bleeding following dengue virus infection occurs due to multiple mechanisms including platelet activation by NS1, serotonin, and PAF, accompanied by a wide range of other coagulation abnormalities.

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9. wwwnc.cdc.gov › eid › articleRetrospective Genomic Characterization of a 2017 Dengue Virus ...

   wwwnc.cdc.gov › eid › article

   Nucleotide identity between dengue virus molecular diagnostics and all sequenced DENV genomes from the 2017 Burkina Faso dengue outbreak. The map indicates the proportion of genomes from each country with >1 mismatches against the Trioplex PCR forward primer (A), probe (B), and reverse1 primer (C).