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Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.
- Figure - PMC - National Center for Biotechnology Information
The pathogenesis of dengue virus infection is attributed to...
- Dengue virus infection: current concepts in immune mechanisms ...
Dengue viruses (DENV), a group of four serologically...
- Figure - PMC - National Center for Biotechnology Information
Jan 24, 2019 · Dengue is a viral illness that is spread primarily by Aedes mosquitoes and infects ~390 million people each year worldwide 1.It is caused by dengue virus (DENV), which belongs to the family of ...
- Ashley L St John, Ashley L St John, Abhay P S Rathore
- 2019
Oct 10, 2018 · Dengue virus (DENV) is a mosquito-borne Flavivirus that is endemic in many tropical and sub-tropical countries where the transmission vectors Aedes spp. mosquitoes resides. There are four serotypes of the virus. Each serotype is antigenically different, meaning they elicit heterologous antibodies. Infection with one serotype will create ...
- Naoko Uno, Ted M. Ross
- 10.1038/s41426-018-0168-0
- 2018
- Emerg Microbes Infect. 2018; 7: 167.
Jan 15, 2023 · The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human, causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar conserved structure and sequence among distinct DENV serotypes or different flaviviruses has resulted in the occurrence of cross reaction followed by antibody-dependent enhancement (ADE).
Jan 20, 2024 · Introduction. Dengue (DENV) is a virus that poses a serious threat to global health as the etiological agent of dengue fever. Four distinct serotypes have been reported (DENV-1 to -4) which differ ...
May 1, 2024 · HLH is characterized by macrophage activation, natural killer (NK) cell dysfunction and depletion, and aberrant T cell activation leading to a cytokine storm [ 122 ]. HLH leading to severe dengue is one of the most important challenges in managing patients with dengue because it is associated with high mortality.
