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May 26, 2022 · Overview. Dengue fever is a mosquito-borne viral disease caused by 1 of 4 antigenically distinct dengue flaviviruses: dengue virus 1 (DEN-1), dengue virus 2 (DEN-2), dengue virus 3 (DEN-3), and dengue virus 4 (DEN-4). The Aedes aegypti mosquito transmits the virus while ingesting a blood meal. Primary viral infection occurs with any of the 4 ...
Aug 22, 2018 · 1. Dengue virus infection and clinical presentation. Dengue virus (DENV) is a vector-borne human pathogen that belongs to the family of Flaviviridae. The disease caused by DENV is considered to be one of the most important human viral maladies of the twenty-first century with nearly 390 million infections annually worldwide in recent years .
- Abhay P. S. Rathore, Ashley L. St. John, Ashley L. St. John
- 10.1098/rsob.180087
- 2018
- Open Biol. 2018 Aug; 8(8): 180087.
- What Is Dengue?
- Who Gets Dengue?
- What Causes Dengue?
- What Are The Clinical Features of Dengue?
- What Are The Complications of Dengue?
- How Is Dengue Diagnosed?
- What Is The Differential Diagnosis For Dengue?
- What Is The Treatment of Dengue?
- Prevention of Dengue
Dengue, or dengue fever, is a viral illness transmitted by the bite of any of dengue viruses. Patients with dengue usually present with fever, headache, rash, nausea, vomiting, aches and pains. In some cases, dengue can progress to a severe form named severe dengue (previously known as dengue haemorrhagic fever), characterised by plasma leakage wit...
Several hundred years ago, dengue virus probably shifted from a mosquito-monkey-mosquito cycle of transmission to becoming endemicin humans. There are an estimated 400 million infectionsin more than 100 countries around the world every year, especially in tropical areas. Children, the elderly and immunosuppressed individuals tend to be more prone t...
Dengue virus belongs to the family of Flavivirus, the same family of viruses including yellow fever and zika. They are also called arboviruses, because are transmitted by arthropod bites (in the case of dengue by the Aedes mosquitoes, especially Aedes aegypti). Dengue viruses (DENV) are small, spherical, single-stranded enveloped RNAviruses with fo...
A person infected by the dengue virus develops severe flu-like symptoms. The clinical features of dengue fever vary according to the characteristics of the infected individual. Symptoms usually last for 2–7 days, after an incubationperiod of 4–10 days after the bite from an infected mosquito [1,3]. In 2009, WHO re-classified dengue infections as de...
The most feared complication of dengue is its severe form. Major bleeding, profound shock, multiple organ failure and brain or heart damage can usually lead to death when present. This is fortunately uncommon .
Dengue infection is diagnosed by testing blood samples during the first 5 days of symptoms and/or early recovery phase (more than 5 days of symptoms) confirming the presence of the virus. The diagnosis can also be confirmed by: 1. The presence of IgM against dengue virus (IgM is an antibodyproduced in acute infections); or; 2. The increase in IgG t...
This can be infectious (mostly) or non-infectious conditions. Infectious conditions 1. Viruses: chikungunya, zika, influenza, acute human immunodeficiency virus (HIV) infection, measles, rubella 2. Bacteria: leptospirosis, typhoid fever, typhus, bacterial sepsis, scarlet fever 3. Protozoa: malaria Non-infectious conditions 1. Inflammatory: systemic...
There is no specific treatment for dengue fever. Patients should seek medical advice, rest and drink plenty of fluids. 1. Paracetamol can be taken to bring down fever and reduce joint pains. 2. Aspirin or non-steroidal anti-inflammatories (NSAIDs) such as ibuprofen should not be taken since they can increase the risk of bleeding [1,5]. In the case ...
There is ongoing research about medications and vaccines against dengue virus, and also for reduction and/or elimination of Aedes mosquitoes [1,6].
Oct 5, 2022 · Dengue virus infection. Picture 2. Headache, eye pain (ie, pain with eye movement), and joint pain occur in 60 to 70 percent of cases [ 24 ]. Rash occurs in approximately half of cases; it is more common during primary infection than secondary infection.
Nov 24, 2020 · There are a lot of promising areas in this field which could be progressed like animal experimentation, examining the direct effect of dengue virus NS1 antigen on capillary permeability and also the association of NS1 levels with disease severity. This will help us to understand the role of NS1 antigen and its association with disease severity.
- Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
- 10.1007/s00284-020-02284-w
- 2021
- Curr Microbiol. 2021; 78(1): 17-32.
Summary: Much remains to be learned about the pathogenesis of the different manifestations of dengue virus (DENV) infections in humans. They may range from subclinical infection to dengue fever, dengue hemorrhagic fever (DHF), and eventually dengue shock syndrome (DSS). As both cell tropism and tissue tropism of DENV are considered major ...
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The dengue virus is a roughly spherical structure composed of the viral genome and capsid proteins surrounded by an envelope and a shell of proteins. After infecting a host cell, the dengue virus ...
