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Mar 1, 2017 · Consequently, drugs directed at the viral targets or critical host mechanisms that can be used safely as prophylaxis or treatment to effectively ameliorate disease or reduce disease severity and fatalities are still needed to reduce the burden of dengue.
Apr 18, 2023 · Currently, the drugs are in phase 1 (NCT05366439) and phase 2 (NCT05466240) double-blind, randomized, placebo-controlled studies to assess the safety and antiviral activity in the dengue human challenge model and in dengue patients, respectively.
- 10.1007/s40506-023-00263-w
- 2023
Mar 8, 2023 · Anti-DENV drug candidates such as chloroquine, prednisolone, lovastatin, and celgosivir have undergone clinical trials but failed to reduce viremia significantly to provide any significant beneficial effects [ 17, 18, 19, 20 ].
- 10.3390/v15030705
- 2023/03
- Viruses. 2023 Mar; 15(3): 705.
Mar 7, 2024 · There are four dengue virus (DENV) types (DENV-1, DENV-2, DENV-3, and DENV-4), all of which are capable of inducing severe disease (dengue hemorrhagic fever [DHF]/dengue shock syndrome [DSS]).
Compare risks and benefits of common medications used for Dengue Fever. Find the most popular drugs, view ratings and user reviews.
Nov 16, 2022 · Medication Summary. No specific antiviral medication is available to treat dengue. The treatment of dengue fever is symptomatic and supportive in nature. Bed rest and mild...
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Oct 6, 2021 · An effective drug against dengue virus (DENV) is urgently needed, because this mosquito-transmitted virus represents a tremendous public-health burden, with about 3.9 billion people at risk of...