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  1. Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.

  2. Dec 15, 2021 · Phospholipase A 2, a chemical constituent of Crotalus durissus terrificus venom, was inhibited dengue virus and yellow fever virus infection in Vero cells, inducing a partial exposure of genomic RNA through glycerophospholipids cleavage . Tomatidine has inhibited dengue virus mainly at late stages of infection towards all dengue virus serotypes ...

    • 10.1155/2021/4224816
    • 2021
    • Biomed Res Int. 2021; 2021: 4224816.
  3. The OpenDengue dataset contains reported total case counts with each row corresponds to a unique location and time. Where reported, we include dengue cases at all levels of severity (dengue, dengue with/without warning signs, severe dengue, dengue haemorhaggic fever, dengue shock syndrome, dengue deaths) and methods of confirmation (suspected ...

  4. DEN Dengue DEN-1 Dengue virus serotype 1 DEN-2 Dengue virus serotype 2 DEN-3 Dengue virus serotype 3 DEN-4 Dengue virus serotype 4 DF Dengue fever DHF Dengue haemorrhagic fever DIVC Disseminated intravascular coagulopathy DSS Dengue shock syndrome DPG Diphosphoglycerate ECG Electrocardiogram

  5. Apr 12, 2012 · VOL. 366 NO. 15. Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a public health challenge with an ...

  6. Apr 22, 2024 · Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of the Aedes species. In the majority of individuals, the infection is asymptomatic, and the immune ...

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  8. May 1, 2024 · HLH is characterized by macrophage activation, natural killer (NK) cell dysfunction and depletion, and aberrant T cell activation leading to a cytokine storm [ 122 ]. HLH leading to severe dengue is one of the most important challenges in managing patients with dengue because it is associated with high mortality.

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