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  1. Oct 12, 2021 · Overall, reduced RBC count has no diagnostic or prognostic power for sepsis. Basic CBC provides several parameters related to RBC characteristics, including hemoglobin (Hb), hematocrit, mean cell (or corpuscular) volume (MCV), mean corpuscular hemoglobin (MCH), mean cell hemoglobin concentration (MCHC), and red distribution width (RDW).

    • Figure 2

      The CBC of an adult patient with sepsis. WBC, white blood...

    • Table 1

      Sepsis represents an important global health burden due to...

  2. Nov 30, 2019 · The complete blood count has long been an integral component of diagnosing septic shock. For example, the initial definition of systemic inflammatory response syndrome (SIRS) in 1992 included abnormality in white blood cell count (either elevated or reduced) or a normal white blood cell count with >10% bands ( 1 ).

    • Joshua David Farkas
    • 10.21037/jtd.2019.12.63
    • 2020
    • J Thorac Dis. 2020 Feb; 12(Suppl 1): S16-S21.
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  4. Oct 13, 2020 · The dataset already contained the sex and age features, while we deduced the septic episode feature by selecting all the patients that already had a sepsis before the surgery (“Preop shock = 1...

    • Davide Chicco, Giuseppe Jurman
    • 2020
  5. Apr 1, 2020 · Sepsis-induced hypothermia and the absence of fever are more likely in older adults and in people with chronic alcohol abuse or immunosuppression. 33 Hypotension is the presenting abnormality in ...

  6. The results showed that compared with high-dose hemoglobin, the low-dose group had a reduced risk of a poor prognosis of sepsis (OR = 1.78, 95 % CI: 1.272.48, P = 0.0008, Fig. 4 ). Further dose-response meta-analysis showed that the risk of poor prognosis of sepsis decreased with increasing hemoglobin.

  7. Sepsis in older adults has many challenges that affect rate of septic diagnosis, treatment, and monitoring parameters. Numerous age-related changes and comorbidities contribute to increased risk of infections in older adults, but also atypical symptomatology that delays diagnosis.

  8. The single most useful parameter from the blood count might be the NLR, given its early responsiveness to infection and unidirectional response to physiologic stress (unlike the white blood cell count, which may either rise or fall in septic shock).

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