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  1. Oct 13, 2020 · Sepsis is a life-threatening condition caused by an exaggerated reaction of the body to an infection, that leads to organ failure or even death. Since sepsis can kill a patient even in just one ...

    • Davide Chicco, Giuseppe Jurman
    • 2020
  2. Oct 12, 2021 · Overall, reduced RBC count has no diagnostic or prognostic power for sepsis. Basic CBC provides several parameters related to RBC characteristics, including hemoglobin (Hb), hematocrit, mean cell (or corpuscular) volume (MCV), mean corpuscular hemoglobin (MCH), mean cell hemoglobin concentration (MCHC), and red distribution width (RDW).

    • Luisa Agnello, Rosaria Vincenza Giglio, Giulia Bivona, Concetta Scazzone, Caterina Maria Gambino, Al...
    • 10.3390/diagnostics11101881
    • 2021
    • Diagnostics (Basel). 2021 Oct; 11(10): 1881.
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  4. May 31, 2019 · In this study, low hemoglobin levels (<9.0 g/dl) were observed in approximately 20% of patients with septic shock, and the severity of decrease in these levels correlated with mortality. However, transfusion itself was not an independent factor affecting mortality. These findings suggest that initial hemoglobin levels may play a role as a ...

    • Sung Min Jung, Youn-Jung Kim, Seung Mok Ryoo, Won Young Kim
    • 2019
  5. Jul 16, 2021 · The area under the curve (AUC) in ROC analysis for prediction of mortality with continuous NRBC results was 0.60 (95% CI, 0.57–0.63) for the whole study cohort and 0.58 (95% CI, 0.55–0.62) for patients with confirmed sepsis. There were 60 patients with pre-existing hematologic disease of whom seven died (11.7%).

    • Erik K. Amundsen, Erik K. Amundsen, Christina Binde, Erik E. Christensen, Erik E. Christensen, Olav ...
    • 10.1097/CCE.0000000000000490
    • 2021
    • Crit Care Explor. 2021 Jul; 3(7): e0490.
  6. Anemia is a major problem in sepsis patients. Low hemoglobin values at admission may indicate chronic anemia, an acute drop in hemoglobin levels caused by sepsis, or a combination of the two.1 The consequences of sepsis on red blood cells include reduced antioxidant status, changed hemoglobin and oxygen affinity, altered red blood cell size and shape, and altered deformability. Anemia can also ...

  7. Feb 20, 2024 · Among studies that evaluated the diagnostic ability of EWS to predict in-hospital mortality in sepsis, two studies used the clinical criteria of the sepsis-3 definition as the basis of their sepsis diagnosis (Boonmee et al., 2020; Khwannimit et al., 2019) and two studies used the sepsis definition of presence of infection with at least one ...

  8. Oct 12, 2021 · Sepsis represents an important global health burden due to its high mortality and morbidity. The rapid detection of sepsis is crucial in order to prevent adverse outcomes and reduce mortality. However, the diagnosis of sepsis is still challenging and many efforts have been made to identify reliable biomarkers. Unfortunately, many investigated biomarkers have several limitations that do not ...

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