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  1. Oct 12, 2021 · Overall, reduced RBC count has no diagnostic or prognostic power for sepsis. Basic CBC provides several parameters related to RBC characteristics, including hemoglobin (Hb), hematocrit, mean cell (or corpuscular) volume (MCV), mean corpuscular hemoglobin (MCH), mean cell hemoglobin concentration (MCHC), and red distribution width (RDW).

    • Figure 2

      The CBC of an adult patient with sepsis. WBC, white blood...

    • Table 1

      Sepsis represents an important global health burden due to...

  2. Oct 13, 2020 · The dataset already contained the sex and age features, while we deduced the septic episode feature by selecting all the patients that already had a sepsis before the surgery (“Preop shock =...

    • Davide Chicco, Giuseppe Jurman
    • 2020
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  4. May 31, 2019 · Low hemoglobin levels are frequently observed in patients with septic shock and may have several underlying causes, including reduced red blood cell (RBC) production due to systemic inflammatory response and increased RBC destruction due to hemolysis and bleeding [ 1 ].

    • Sung Min Jung, Youn-Jung Kim, Seung Mok Ryoo, Won Young Kim
    • 2019
  5. WBC count may be decreased (< 4,000/mcL [< 4 × 10 9 /L]) or increased (> 15,000/mcL [> 15 × 10 9 /L]), and polymorphonuclear leukocytes may be as low as 20%. During the course of sepsis, the WBC count may fluctuate, depending on the severity of sepsis or shock, the patient's immunologic status, and the etiology of the infection.

  6. Nov 30, 2019 · With a low cutoff of NLR >3, the test was 96% sensitive but only 10% specific. Raising the cutoff value to NLR >10 improved the specificity to 56%, but at the cost of lowering the sensitivity to 80%.

    • Joshua David Farkas
    • 10.21037/jtd.2019.12.63
    • 2020
    • J Thorac Dis. 2020 Feb; 12(Suppl 1): S16-S21.
  7. Jan 10, 2024 · In sepsis, anemia's multifactorial causes include reduced red blood cell production, stress-induced bleeding, hemodilution, recurrent blood withdrawal, impaired iron metabolism and hemolysis. A study of 815 older septic patients revealed over 20% had hemoglobin levels below 10 g/dL on admission, doubling during the first week.

  8. Oct 12, 2021 · Overall, reduced RBC count has no diagnostic or prognostic power for sepsis. Basic CBC provides several parameters related to RBC characteristics, including hemoglobin (Hb), hematocrit, mean cell (or corpuscular) volume (MCV), mean corpuscular hemoglobin (MCH), mean cell hemoglobin concentration (MCHC), and red distribution width (RDW).

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