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      • Hematologic changes are present in virtually every patient with severe sepsis. Leukocytosis, anemia, thrombocytopenia, and activation of the coagulation cascade are the most common abnormalities.
      www.mayoclinicproceedings.org › article › S0025-6196(11)62688-8
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  2. Oct 12, 2021 · The CBC of an adult patient with sepsis. WBC, white blood cells; RBC, red blood cells; MCV, mean cell volume; MCH, mean corpuscular hemoglobin, MCHC, mean cell hemoglobin concentration, RDW, red distribution width; PLT, platelet. * indicates values out of reference range. Notably, reference ranges change according to the instrument used.

  3. Dec 8, 2023 · Conclusion: The level of hemoglobin at admission is related to the prognosis of patients with sepsis, and decreases in hemoglobin level are associated with an increase in the mortality rate of patients with sepsis.

  4. Key Points. Sepsis is a clinical syndrome of life-threatening organ dysfunction caused by a dysregulated response to infection. In septic shock, there is critical reduction in tissue perfusion and acute failure of multiple organs, including the lungs, kidneys, and liver, can occur.

  5. Oct 12, 2021 · nancy [17,18]. Additionally, WBC count could be normal or even decreased in some cases of sepsis. Thus, total WBC has a poor specificity, which limits its usefulness as a biomarker of sepsis [14]. 3.1.1. Lymphocytes Lymphocytes are key components of the adaptive immune response. They make up approximately 20–40% of the total leukocyte count.

  6. Sepsis with acute organ dysfunction (severe sepsis) results from a systemic proinflammatory and procoagulant response to infection. Organ dysfunction in the patient with sepsis is associated with increased mortality.

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