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Jun 11, 2015 · Nitrofurantoin's use has increased exponentially since recent guidelines repositioned it as first-line therapy for uncomplicated lower urinary tract infection (UTI). We conducted a systematic review and meta-analysis to assess nitrofurantoin's efficacy and toxicity in the treatment of lower UTI.
- Angela Csaki Huttner, Els Verhaegh, Stéphan Juergen Harbarth, Anouk Muller, Ursula Theuretzbacher, J...
- 2015
Jun 15, 2015 · We conducted a systematic review and meta-analysis to assess nitrofurantoin's efficacy and toxicity in the treatment of lower UTI. Methods: We performed a systematic review of all human controlled clinical trials published from 1946 to 2014 and assessing short-term (≤14 days) nitrofurantoin for lower UTI. Meta-analyses assessing efficacy and ...
- Angela Csaki Huttner, Els Verhaegh, Stéphan Juergen Harbarth, Anouk Muller, Ursula Theuretzbacher, J...
- 2015
Nitrofurantoin has remained effective after more than 50 years of extensive use worldwide with essentially no resistance, and for initial empiric therapy for uncomplicated community-acquired or nosocomial UTIs, nitrofurantoin is an ideal antibiotic.
- Burke A. Cunha, Paul E. Schoch, Jean R. Hage
- 2011
May 29, 2023 · Nitrofurantoin is an antibiotic medication that is used for the treatment of uncomplicated lower urinary tract infections. It is effective against most gram-positive and gram-negative organisms. Nitrofurantoin’s primary use has remained in treating and prophylaxis of urinary tract infections.
- Francis J. Squadrito, Daniel del Portal
- 2023/05/29
Aug 18, 2016 · When compared with no prophylaxis, nitrofurantoin is effective in the prevention of UTI (risk ratio 0.38 in favour of nitrofurantoin, 95% CI 0.30–0.48). Its prophylactic efficacy is superior to that of methenamine hippurate and comparable to that of other antibacterials.
- Anouk E Muller, Els M Verhaegh, Stéphan Juergen Harbarth, Johan W Mouton, Angela Csaki Huttner
- 2017
Sep 1, 2015 · Nitrofurantoin revisited: a systematic review and meta-analysis of controlled trials. Nitrofurantoin appears to have good clinical and microbiological efficacy for UTI caused by common uropathogens, with clinical cure rates varying between 79% and 92%.
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Can nitrofurantoin be used as a prophylaxis for urinary tract infections?
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Nitrofurantoin revisited: a systematic review and meta-analysis of controlled trials | Oxford Academic. Table 1. Inclusion criteria for studies considered for the review of nitrofurantoin's efficacy and toxicity for therapy of lower UTI.
