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      • This systematic review evaluates the evidence for the effectiveness of the Neonatal Early-Onset Sepsis Calculator (EOScalc) as a screening tool to appropriately identify neonatal early-onset sepsis and the ability to decrease unnecessary antibiotic use in late preterm and term infants.
      journals.lww.com › jpnnjournal › Abstract
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  2. The Kaiser Permanente neonatal early-onset sepsis calculator ( https://neonatalsepsiscalculator.kaiserpermanente.org) is a tool designed to improve the selection of neonates with suspected...

  3. Sep 3, 2019 · The purpose of the current systematic review and meta-analysis was to identify, critically appraise, and synthesize evidence from studies comparing management guided by the EOS calculator with conventional management strategies, and report the rates of empirical antibiotic therapy for suspected EOS.

    • Niek B. Achten, Claus Klingenberg, William E. Benitz, Martin Stocker, Luregn J. Schlapbach, Luregn J...
    • 10.1001/jamapediatrics.2019.2825
    • 2019
    • JAMA Pediatr. 2019 Nov; 173(11): 1032-1040.
  4. Association of Use of the Neonatal Early-Onset Sepsis Calculator With Reduction in Antibiotic Therapy and Safety: A Systematic Review and Meta-analysis | Neonatology | JAMA Pediatrics | JAMA Network. Flowchart of search results and study selection. a Studies excluded because data set was used in early-onset sepsis calculator development.

    • Niek B. Achten, Claus Klingenberg, William E. Benitz, Martin Stocker, Luregn J. Schlapbach, Luregn J...
    • 2019
  5. Apr 21, 2021 · Kaiser Permanente Calculator (KPC) or EOS risk calculator is an advanced multivariate risk model for predicting EOS in infants. Objective. To examine the EOS risk calculator effect for predicting neonatal EOS, the necessity for laboratory tests, antibiotic usage, and length of hospital stay among the term and late-preterm newborns. Method.

    • Roya Huseynova, Latifa Bin Mahmoud, Fahad Hamad Aljobair, Ogtay Huseynov, Halima Career, Parameaswar...
    • 10.7759/cureus.14620
    • 2021
    • Cureus. 2021 Apr; 13(4): e14620.
  6. Aug 11, 2022 · Neonatal Early Onset Sepsis (EOS) Calculator plus Universal Serial Physical Examination (SPE): A Prospective Two-Step Implementation of a Neonatal EOS Prevention Protocol for Reduction of Sepsis Workup and Antibiotic Treatment.

  7. EOS calculator (P < .01). Of these 90/890 (10.1%) children, antibiotic treatment was recommended by both methods, including the two neonates with positive blood cultures. Our findings echo the results of a systematic review and me-ta-analysis of retrospective and prospective studies on the EOS

  8. Mar 25, 2021 · PMCID: PMC7992929. DOI: 10.1186/s13052-021-01028-1. Abstract. Background: According to most early-onset sepsis (EOS) management guidelines, approximately 10% of the total neonatal population are exposed to antibiotics in the first postnatal days with subsequent increase of neonatal and pediatric comorbidities.

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