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1. en.wikipedia.org › wiki › Why_Most_PublishedWhy Most Published Research Findings Are False - Wikipedia

   en.wikipedia.org › wiki › Why_Most_Published

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   Given the realities of bias, low statistical power, and a small number of true hypotheses, Ioannidis concludes that the majority of studies in a variety of scientific fields are likely to report results that are false.

2. Videos

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     Perspectives on the Pandemic | Dr. John Ioannidis Update: 4.17.20 | Episode 4

     Apr 20, 2020

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     56:12

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     Is Reproducible Research Accurate? | John Ioannidis | Talks at Google

     Jun 11, 2014

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     23:55

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     John Ioannidis - Why most clinical research is not useful

     Aug 11, 2016

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3. journals.plos.org › plosmedicine › articleWhy Most Published Research Findings Are False | PLOS Medicine

   journals.plos.org › plosmedicine › article

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   Aug 30, 2005 · Published research findings are sometimes refuted by subsequent evidence, says Ioannidis, with ensuing confusion and disappointment.

   • Author: John P. A. Ioannidis

   • Publish Year: 2005

4. www.scientificamerican.com › article › the-ioannidisThe Ioannidis Affair: A Tale of Major Scientific Overreaction

   www.scientificamerican.com › article › the-ioannidis

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   Nov 30, 2020 · Ioannidis estimated that deaths in the U.S. from COVID-19 could potentially be as low as 10,000—or they could approach levels not seen since the flu pandemic of 1918. Anything was possible, he...

5. med.stanford.edu › profiles › john-ioannidisJohn P.A. Ioannidis | Stanford Medicine

   med.stanford.edu › profiles › john-ioannidis

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   Current Research and Scholarly Interests. My work is trying to optimize the chances of getting more reliable, trustworthy, and useful research. I have worked in the fields of evidence-based medicine, clinical investigation, clinical and molecular epidemiology, clinical research methodology, empirical research methods, statistics, and genomics.

6. www.ncbi.nlm.nih.gov › pmc › articlesWhy Most Published Research Findings Are False - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Aug 30, 2005 · It can be proven that most claimed research findings are false. As has been shown previously, the probability that a research finding is indeed true depends on the prior probability of it being true (before doing the study), the statistical power of the study, and the level of statistical significance [ 10, 11 ].

7. scholar.google.com › citations‪John P.A. Ioannidis‬ - ‪Google Scholar‬

   scholar.google.com › citations

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   John P.A. Ioannidis. Professor of Medicine/Health Research & Policy/Biomedical Data Science/Statistics, Stanford Univ. Verified email at stanford.edu - Homepage. meta-research clinical epidemiology evidence-based medicine research methods meta-analysis.

8. People also ask

   Did Ioannidis prove that most research findings are false?

   • Ioannidis's use of dramatic and exaggerated language that he "proved" that most research findings' claims are false and that "most research findings are false for most research designs and for most fields " [italics added] was rejected, and yet they agreed with his paper's conclusions and recommendations.

   Why Most Published Research Findings Are False - Wikipedia

   en.wikipedia.org/wiki/Why_Most_Published_Research_Findings_Are_False

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   What problems did John Ioannidis raise about the design of a study?

   • Fourth, the authors did not disclose that there were other problematic issues raised about the design of a study co-authored by John Ioannidis, most notably how the study authors recruited study participants and how independent faculty at Stanford said that they were unable to verify the accuracy of their test.

   The Ioannidis Affair: A Tale of Major Scientific Overreaction

   www.scientificamerican.com/article/the-ioannidis-affair-a-tale-of-major-scientific-overreaction/

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   Did Ioannidis have a 'contrarian position'?

   • Richard Ebright, a professor of chemistry and chemical biology at Rutgers University, tweeted that Ioannidis’ STAT essay was “content-free, logic-free drivel.” James P. Reichmann, a student of public health at Georgia State University, wrote that Ioannidis’ “contrarian position” could cause “ irreparable harm ” and cost “thousands of human lives.”

   The Ioannidis Affair: A Tale of Major Scientific Overreaction

   www.scientificamerican.com/article/the-ioannidis-affair-a-tale-of-major-scientific-overreaction/

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9. dspace.mit.edu › contents › readingsEssay Why Most Published Research Findings Are False

   dspace.mit.edu › contents › readings

   Why Most Published Research Findings Are False John P. A. Ioannidis ; when ; Summary There is increasing concern that most current published research fi ndings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio