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  1. Sep 29, 2022 · Late-onset sepsis (LOS) usually occurs via the transmission of pathogens from the surrounding environment after delivery, such as contact from healthcare workers or caregivers. A percentage ofLOS may also be caused by a late manifestation of vertically transmitted infection.

  2. Nov 1, 2022 · Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

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  4. Late (after 3 days) Early-onset neonatal sepsis usually results from organisms acquired intrapartum. Most infants have symptoms within 6 hours of birth. Most cases are caused by group B streptococcus (GBS) and gram-negative enteric organisms (predominantly Escherichia coli).

  5. Nov 2, 2011 · This guideline addresses the evaluation of NICU infants for hospital-acquired infection (also referred to as late-onset sepsis or nosocomial sepsis, occurring at > 72 hours of age.)

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  6. Jan 6, 2020 · Late onset sepsis (LOS; i.e., sepsis onset >72 h after birth) remains a leading cause of neonatal mortality . It often presents with nonspecific signs of illness (e.g., temperature instability ...

    • V Lamba, S D'souza, C Carafa, A Zepf, C L Bassel, M Gutierrez, M Balakrishnan
    • 2020
  7. Apr 1, 2021 · Neonatal infection is a significant cause of mortality and morbidity in newborn babies. It can lead to life-threatening sepsis, which accounts for 10% of all neonatal deaths. Late-onset neonatal infection (infection that occurs more than 72 hours after birth), is present in 7 of every 1000 newborn babies and is responsible for 61 of every 1000 ...

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