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  1. Aug 8, 2023 · Mononucleosis classically presents with fever, lymphadenopathy, and tonsillar pharyngitis. The term “infectious mononucleosis” was first used in the 1920s to describe a group of students with a similar pharyngeal illness and blood laboratory findings of lymphocytosis and atypical mononuclear cells. It was only later that Epstein-Barr virus (EBV) was established as the cause of ...

  2. May 27, 2010 · The Clinical Problem. Infectious mononucleosis is a clinical syndrome that is most commonly associated with primary Epstein–Barr virus (EBV) infection. EBV is a gamma herpesvirus with a double ...

  3. Jul 27, 2023 · INFECTIOUS MONONUCLEOSIS OVERVIEW. Infectious mononucleosis, also known as "mono" or the "kissing disease," is an infection that typically causes fever, sore throat, fatigue, and/or enlarged lymph nodes in the neck. It most commonly occurs in adolescents and young adults. In general, mononucleosis is not considered a serious illness.

  4. In wealthier nations, infectious mononucleosis mostly affects adolescents and young adults 15 to 24 years of age (6 to 8 cases per 1,000 person-years), particularly those living in communal ...

  5. In most young children, primary EBV infection is asymptomatic. Symptoms of infectious mononucleosis develop most often in older children and adults. The incubation period is about 30 to 50 days. Fatigue can last for months but is usually maximal during the first 2 to 3 weeks. Most patients have the triad of. Fever. Pharyngitis. Adenopathy

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