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Paul Ehrlich ( German: [ˈpaʊl ˈʔeːɐ̯lɪç] ⓘ; 14 March 1854 – 20 August 1915) was a Nobel Prize -winning German physician and scientist who worked in the fields of hematology, immunology, and antimicrobial chemotherapy.
German biochemist Paul Ehrlich (1854–1915) developed a chemical theory to explain the body’s immune response and did important work in chemotherapy, coining the term magic bullet. Ehrlich received the Nobel Prize in Physiology or Medicine in 1908.
Feb 5, 2016 · Paul Ehrlich's contributions to science undoubtedly paved the way to a new era of medicine, where cellular features and functions were linked to specific molecules, and translational concepts were established based on mechanistic and molecular insights into the pathophysiology of the disease and specific molecular interactions, including drug ...
- Peter Valent, Bernd Groner, Udo Schumacher, Giulio Superti-Furga, Meinrad Busslinger, Robert Kralovi...
- 10.1159/000443526
- 2016
- J Innate Immun. 2016 Mar; 8(2): 111-120.
Paul Ehrlich was a German medical scientist known for his pioneering work in hematology, immunology, and chemotherapy and for his discovery of the first effective treatment for syphilis. He received the Nobel Prize for Physiology or Medicine in 1908 jointly with Élie Metchnikoff.
Feb 5, 2016 · In a pioneering effort to detect drugs capable of specifically killing certain microbes, Ehrlich synthesized a series of specific antimicrobial drugs, the most famous example being arsphenamine (Salvarsan®), the first synthetic agent against syphilis [ 5 ].
Ehrlich had, like so many other discoverers before him, to battle with much opposition before Salvarsan or Neosalvarsan were accepted for the treatment of human syphilis; but ultimately the practical experience prevailed and Ehrlich became famous as one of the main founders of chemotherapy.
During his clinical work, Paul Ehrlich treated a patient with paroxysmal hemoglobinuria and reported his diagnostic approaches, including those related to erythrocyte lysis and microscopic cell analysis, to the Verein für Innere Medicine/Society of Internal Medicine, Berlin.
