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Oct 14, 2021 · 1-Phenylcyclohexylamine | C12H17N | CID 31862 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
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- 1959/09/22
- MONSANTO (J. FREEMAN)
- N-cyclohexylanilineN-cyclohexyl-N-phenylamine
- COBLENTZ NO. 08474
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Alkylation is an efficient method for the synthesis of 3 o and 4 o amines. However, when 1 o and 2 o amines are alkylated a mixture of products is typically produced. When ammonia is reacted with an alkylhalide an monoalkylammonium salt is formed. RX + NH 3 → RNH 3+ + X -.
Jan 1, 2016 · The first arylcyclohexamine to be described was 1-(1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP . Other analogues reported in the early 1950s included N-ethyl-1-phenylcyclohexylamine (PCE) and 1-(1-phenylcyclohexyl)morpholine (PCMo). While many were not explored further by their initial investigators, chemists ...
thesis of 1-phenylcyclohexylamine. The compound prepared by the alternate route (method F) was identi- cal in all respects with the one obtained prepared from Method F aC6"I NCO - CxCeH5 "2 VI phenylcyclohexene. Recently, Cristol, et ul., re- ported the isolation of the amine as its benzoyl deriva- tive via a modified Ritter reaction.
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Various 1-arylcyclohexylamines were synthesized for evaluation as central nervous system depressants and tested for cataleptoid activity and antitonic extensor properties. Various 1-arylcyclohexylamines were synthesized for evaluation as central nervous system depressants. The compounds were prepared by several procedures. 1-(1-Phenylcyclohexyl)piperidine, the first compound of this type ...
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