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2. chem.libretexts.org › Bookshelves › Organic_Chemistry24.6: Synthesis of Amines - Chemistry LibreTexts

   chem.libretexts.org › Bookshelves › Organic_Chemistry

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   Example. Planning a Synthesis using a Hoffman or Curtius Rearrangement. Because the amide and the acyl azide required for these rearrangements both are best made from an acid chloride, synthesis of amines using these reaction are best started from the corresponding carboxylic acid.

3. www.erowid.org › archive › rhodiumThe Synthesis of Phencyclidine and Other 1 ... - Erowid

   www.erowid.org › archive › rhodium

   thesis of 1-phenylcyclohexylamine. The compound prepared by the alternate route (method F) was identi- cal in all respects with the one obtained prepared from Method F aC6"I NCO - CxCeH5 "2 VI phenylcyclohexene. Recently, Cristol, et ul., re- ported the isolation of the amine as its benzoyl deriva- tive via a modified Ritter reaction.

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   What was the first arylcyclohexamine?

   • The first arylcyclohexamine to be described was 1- (1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP [ 1 ]. Other analogues reported in the early 1950s included N -ethyl-1-phenylcyclohexylamine (PCE) and 1- (1-phenylcyclohexyl)morpholine (PCMo).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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   How many substituted 1 phenylcyclohexyl pyrrolidine analogues are there?

   • The present study describes the synthesis of three substituted 1- (1-phenylcyclohexyl)piperidines, (3-MeO-, 4-MeO- and 3-Me-PCP) and three substituted 1- (1-phenylcyclohexyl)pyrrolidine analogues (3-MeO-, 4-MeO- and 3-Me-PCPy).

   Preparation and analytical characterization of 1‐(1‐phenylcyclohexyl)pip…

   analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/dta.1468

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   What are arylcyclohexamines?

   • Arylcyclohexamines (also known as arylcyclohexylamines) are a group of compounds that contain a cyclohexamine unit with an aryl moiety, typically a phenyl ring, attached to the same atom to which the amine group is linked (see Fig. 1 ).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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   Are there any arylcyclohexamine analogues?

   • The only case series of other arylcyclohexamine analogues comes from the Swedish STRIDA project, which reported 59 cases of acute 3- and 4-MeO-PCP toxicity [ 101 ]; 86.4 % were male and the median age was 26 years.

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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5. pubchem.ncbi.nlm.nih.gov › 1-phenylcyclohexylamine1-Phenylcyclohexylamine | C12H17N | CID 31862 - PubChem

   pubchem.ncbi.nlm.nih.gov › 1-phenylcyclohexylamine

   Oct 14, 2021 · 1-Phenylcyclohexylamine | C12H17N | CID 31862 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

6. webbook.nist.gov › cgi › cbookN-Phenylcyclohexylamine - NIST Chemistry WebBook

   webbook.nist.gov › cgi › cbook

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   For Zoom; 1.) Enter the desired X axis range (e.g., 100, 200) 2.) Check here for automatic Y scaling 3.) Press here to zoom

   • Date: 1959/09/22
   • Origin: MONSANTO (J. FREEMAN)

   • Name(s): N-cyclohexylanilineN-cyclohexyl-N-phenylamine
   • Source reference: COBLENTZ NO. 08474

7. link.springer.com › referenceworkentry › 10Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com › referenceworkentry › 10

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   Jan 1, 2016 · The most well-characterized arylcyclohexamines are phencyclidine ( (1- (1-phencyclohexyl) piperidine; PCP )), ketamine, and, of the novel analogues, methoxetamine. Fig. 1. Chemical structures of the primary arylcyclohexamines: phencyclidine , ketamine , and methoxetamine. Full size image.

8. analyticalsciencejournals.onlinelibrary.wiley.comPreparation and analytical characterization of 1‐(1 ...

   analyticalsciencejournals.onlinelibrary.wiley.com

   Apr 2, 2013 · Preparation and analytical characterization of 1‐ (1‐phenylcyclohexyl)piperidine (PCP) and 1‐ (1‐phenylcyclohexyl)pyrrolidine (PCPy) analogues - Wallach - 2014 - Drug Testing and Analysis - Wiley Online Library.

9. www.semanticscholar.org › paper › Synthesis-andSynthesis and anticonvulsant activity of 1 ... - Semantic Scholar

   www.semanticscholar.org › paper › Synthesis-and

   Several analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, exhibited a greater separation of potencies in the motor toxicity and MES seizure tests than did the parent compound PCA. Thirty-eight analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, were examined for their activities in the mouse maximal electroshock (MES) seizure test and in a ...