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  1. Samantha Who? (TV Series 2007–2009) cast and crew credits, including actors, actresses, directors, writers and more.

  2. Cecelia Ahern. Donald Todd. Stars. Christina Applegate. Jennifer Esposito. Kevin Dunn. See production info at IMDbPro. STREAMING. RENT/BUY. from $9.79. search Amazon. Add to Watchlist.

    • (11K)
    • 2007-10-15
    • Comedy, Mystery, Romance
    • 22
  3. (Top) Plot. Production history. Cast and characters. Episodes. U.S. television ratings. Standard ratings. Seasonal ratings. Ratings competition. DVD releases. Awards and nominations. Broadcast. References. External links. Samantha Who? is an American television sitcom that originally aired on ABC from October 15, 2007, to July 23, 2009.

    • Sitcom
  4. From left to right: Dena ( Melissa McCarthy ), Howard Newly ( Kevin Dunn ), Regina Newly ( Jean Smart ), Samantha Newly ( Christina Applegate ), Todd Deepler ( Barry Watson ), Andrea Belladonna ( Jennifer Esposito ), Frank ( Tim Russ ). The following is a list of characters in the ABC comedy television series Samantha Who? . Primary characters.

  5. Learn more about the full cast of Samantha Who? with news, photos, videos and more at TV Guide.

    • Lee Shallat Chemel
    • 2
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  7. Jennifer Esposito. Andrea Belladonna. Kevin Dunn. Howard. Melissa McCarthy. Dena. Tim Russ. Frank. Barry Watson. Todd. Watchlist. In Theaters At Home TV Shows. Advertise With Us. Samantha...

  8. Jennifer Esposito. Andrea Belladonna (35 Episodes) Kevin Dunn. Howard (35 Episodes) Melissa McCarthy. Dena (35 Episodes) Tim Russ. Frank (35 Episodes) Barry Watson. Todd (35 Episodes) Jean Smart. Regina Newly (35 Episodes) Rick Hoffman. — (8 Episodes) Kiele Sanchez. — (4 Episodes) James Tupper. — (4 Episodes) Eliza Coupe. — (2 Episodes) Billy Zane.

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