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  1. The goals of resuscitation in sepsis and septic shock are to restore intravascular volume, increase oxygen delivery to tissues, and reverse organ dysfunc-tion. A crystalloid bolus of 30 mL/kg is recom-mended within 3 hours of detecting severe sepsis or septic shock.17 However, only limited.

    • 181KB
    • Siddharth Dugar, Chirag Choudhary, Abhijit Duggal
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    • 2020
  2. Table 1: Antibiotic selection options for healthcare associated and/or immunocompromised patients with severe sepsis/septic shock . Severe Sepsis or Septic Shock (Healthcare associated OR Immunocompromised) Antibacterial A (Select one of the following) Antibacterial B (Select one of the following) +/- Antibacterial C (Select one of the following)

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  3. Oct 4, 2021 · International Guidelines for Management of Sepsis and Septic Shock 2021 Updated global adult sepsis guidelines, released in October 2021 by the Surviving Sepsis Campaign (SSC), place an increased emphasis on improving the care of sepsis patients after they are discharged from the intensive care unit (ICU) and represent greater geographic and gender diversity than previous versions. The new ...

  4. Apr 28, 2023 · Vasopressin (VP) may be considered a second-line choice for septic shock treatment . According to the SSC’s recommendations, it can be administered (at a dose of 0.25–0.5 μg/kg/min) in addition to NE to obtain the target MAP by decreasing the dosage of the latter and reducing the side effects due to adrenergic overload . Furthermore, two ...

  5. May 24, 2024 · Sepsis is a clinical syndrome characterized by a dysregulated host response to infection. There is a continuum of severity ranging from sepsis to septic shock. Although wide-ranging and dependent upon the population studied, mortality has been estimated to be ≥10 percent and ≥40 percent when shock is present [ 1,2 ].

  6. For patients with sepsis induced hypoperfusion or septic shock we suggest that at least 30 mL/kg of IV crystalloid fluid should be given within the first 3 hr of resuscitation. Weak, low quality of evidence. Downgraded from Strong, low quality of evidence “We recommend that in the initial resuscitation from sepsis-induced hypoperfusion, at ...

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  8. septic shock recognition, for patients with a high likelihood of sepsis or possible septic shock. • For patients with possible sepsis but without shock, rapid assessment of an infectious versus non-infectious cause of acute illness is recommended (within 3 hours, when possible). o This includes: History Clinical examination

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