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      • Severe sepsis also includes weakness and signs of organ dysfunction, such as difficulty breathing, low or no urine output, abnormal liver tests, and changes in mental status (like confusion and difficulty rousing). Septic shock has progressed to organ failure and dangerously low blood pressure that’s unresponsive to intravenous fluids.
      thewell.northwell.edu › infectious-disease › 3-stages-of-sepsis
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  2. Jun 14, 2022 · Septic shock describes sepsis complicated by organ failure and blood pressure that remains low despite treatment with fluids. How do you know if you have septic shock? Your healthcare provider may suspect sepsis if you’ve had an infection and you suddenly develop a fever or hypothermia, rapid heart rate or breathing rate, or low blood pressure.

  3. Prognosis |. Key Points. Sepsis is a clinical syndrome of life-threatening organ dysfunction caused by a dysregulated response to infection. In septic shock, there is critical reduction in tissue perfusion and acute failure of multiple organs, including the lungs, kidneys, and liver, can occur.

  4. Oct 27, 2021 · Sepsis is a systemic inflammatory response syndrome (SIRS) caused by either infectious or non-infectious factors. 1–3 It can easily develop into septic shock and multiple organ dysfunction syndromes (MODS) if not treated in a timely manner, and its fatality rate can be as high as 28–56%. 4 Clinically, MODS can be categorized into Phase I immedia...

    • Guo-Dong Sun, Yang Zhang, Shan-Shan Mo, Ming-Yan Zhao
    • 10.2147/IJGM.S328419
    • 2021
    • Int J Gen Med. 2021; 14: 7159-7164.
  5. Nov 20, 2023 · Sepsis or septic shock. This may involve a serious bacterial or viral infection that leads to widespread inflammation. Traumatic injury. This may include a motor vehicle crash, severe burns or a stabbing or gunshot wound. Pancreatitis. Pancreatitis is inflammation of the pancreas.

  6. Feb 10, 2023 · Overview. Sepsis is a serious condition in which the body responds improperly to an infection. The infection-fighting processes turn on the body, causing the organs to work poorly. Sepsis may progress to septic shock. This is a dramatic drop in blood pressure that can damage the lungs, kidneys, liver and other organs.

  7. Septic shock is a subset of sepsis in which underlying cellular metabolism abnormalities are sufficiently profound to significantly increase mortality. Septic shock is clinically recognized as arterial hypotension, refractory to simple fluid resuscitation, with evidence of hyperlactatemia.

  8. MODS is defined as a clinical syndrome characterized by the development of progressive and potentially reversible physiologic dysfunction in 2 or more organs or organ systems that is induced by a...

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