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Where does streptomycin come from?
What is streptomycin used for?
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Streptomycin is an antibiotic medication used to treat a number of bacterial infections, [3] including tuberculosis, Mycobacterium avium complex, endocarditis, brucellosis, Burkholderia infection, plague, tularemia, and rat bite fever. [3] For active tuberculosis it is often given together with isoniazid, rifampicin, and pyrazinamide. [4]
Streptomycin is an aminoglycoside antibiotic, and was the first of these to be discovered in 1943 by Albert Shatz. [1] [2] [3] The use of streptomycin involves the disruption of protein synthesis within the ribosome, preventing replication of bacteria. [4] It arises from the bacteria Streptomyces griseus and is majorly used in the treatment of ...
May 21, 2024 · streptomycin ( uncountable) ( pharmacology) An aminoglycoside and bactericidal antibiotic C 21 H 39 N 7 O 12 that is produced by a soil actinomycete ( Streptomyces griseus ), is active against many bacteria, and is administered via intramuscular injection especially in the treatment of infections by gram-negative bacteria.
Streptomycin is available as an intramuscular injection, and in some cases may be administered intravenously. 2, 3 A peak serum concentration of 25-50 mcg/mL is achieved within 1 hour after intramuscular administration of 1 gram of streptomycin. 20. Volume of distribution. Not Available. Protein binding.
streptomycin: [noun] an antibiotic organic base C21H39N7O12 that is produced by a soil actinomycete (Streptomyces griseus), is active against many bacteria, and is used especially in the treatment of infections (such as tuberculosis) by gram-negative bacteria.
streptomycin: [ strep″to-mi´sin ] an aminoglycoside antibiotic produced by Streptomyces griseus; its use is now limited because of the emergence of resistant strains. The sulfate salt is used in combination with other agents in the treatment of tuberculosis and certain other bacterial infections.
ChEBI. Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s. Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.
