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- Heart valve inflammation from rheumatic fever causes rheumatic heart disease. The damage may occur right away. Or it can develop over time from repeated strep infections. Continuing inflammation leads to heart valve scarring and narrowing. The disease tends to affect the mitral and aortic heart valves. These valves control blood flow.
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Valvular heart disease resulting from rheumatic fever is referred to as rheumatic heart disease. Acute rheumatic fever, which frequently manifests with carditis and valvulitis, is a late sequela of Group A beta-hemolytic streptococcus infection in the throat, often lagging the initial infection by weeks to months.
May 15, 2024 · About 13% of people born before 1943 have valvular heart disease. [1] Rheumatic heart disease most commonly affects the mitral valve (which has only two leaflets; Figure 2) or the aortic valve, but any valve can be affected, and more than one can be involved.
Nov 6, 2020 · The disease results from damage to heart valves caused by one or several episodes of rheumatic fever, an autoimmune inflammatory reaction to throat infection with group A streptococci (streptococcal pharyngitis or strep throat). It most commonly occurs in childhood, and can lead to death or life-long disability.
Rheumatic heart disease is a condition where the heart valves have been permanently damaged by rheumatic fever. The heart valve damage may start shortly after untreated or undertreated streptococcal infection, such as strep throat or scarlet fever. An immune response causes an inflammatory condition in the body.
Jul 22, 2021 · Overview. What is rheumatic heart disease? Rheumatic heart disease is heart valve damage resulting from rheumatic fever. Bacterial infections called group A streptococcal (GAS) infections can cause rheumatic fever. An infection, such as strep throat or scarlet fever, triggers your body’s immune response.
Jan 18, 2021 · Abstract. Rheumatic heart valve disease (RHVD) is a post-infectious sequel of acute rheumatic fever resulting from an abnormal immune response to a streptococcal pharyngitis that triggers valvular damage. RHVD is the leading cause of cardiovascular death in children and young adults, mainly in women from low and middle-income countries.
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