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  1. Jan 6, 2018 · Autism spectrum disorder is a condition related to brain development that impacts how a person perceives and socializes with others, causing problems in social interaction and communication. The disorder also includes limited and repetitive patterns of behavior. The term "spectrum" in autism spectrum disorder refers to the wide range of ...

  2. Aug 20, 2021 · Autism spectrum disorders (ASD) are a group of neurodevelopmental diseases. The cause of ASD is unknown, but several genetic and non-genetic risk factors have been characterized that, alone or in combination, are implicated in the development of ASD. Currently, no diagnostic biomarkers are available, and the diagnosis of ASD is based on typical features that include repetitive behaviors, and ...

    • Ann Katrin Sauer, Janelle E. Stanton, Sakshi Hans, Andreas M. Grabrucker
    • 2021
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  4. Sep 9, 2019 · Definition. Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and the presence of restricted interests and repetitive behaviors ( 1 ). In 2013, the Diagnostic and Statistical Manual of Mental Disorders —5 th edition (DSM-5) was published, updating the diagnostic criteria for ASD ...

    • Holly Hodges, Casey Fealko, Neelkamal Soares
    • 2020
  5. Mar 31, 2021 · Genetic causes of autism. Many experts believe genes play the biggest role in causing autism. A 2019 study estimated that about 80% of autistic people have it due to genetics. Research has found ...

  6. Aug 20, 2019 · Genetic modifiers in autism spectrum disorder. Autism is estimated to be 40–80% heritable. However, both genetic and non-genetic factors modulate the penetrance of risk genes, resulting in a highly heterogeneous disease phenotype for similar pathogenic variants. Examples of genetic modulators include CNV, epigenetics, and double-hit mutations.

    • Lauren Rylaarsdam, Alicia Guemez-Gamboa
    • 10.3389/fncel.2019.00385
    • 2019
    • Front Cell Neurosci. 2019; 13: 385.
  7. Jul 4, 2011 · The study's senior author is Neil Risch, PhD, professor of biostatistics at UC-San Francisco and director of the UCSF Institute for Human Genetics. For years, studies of non-genetic autism risk factors focused on the idea that childhood vaccines might trigger autism, a theory that extensive research did not support.

  8. Nov 15, 2023 · Causes . Available scientific evidence suggests that there are probably many factors that make a child more likely to have autism, including environmental and genetic factors. Extensive research using a variety of different methods and conducted over many years has demonstrated that the measles, mumps and rubella vaccine does not cause autism.