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  2. Nov 11, 2022 · Neonatal late-onset sepsis (LOS) remains a significant cause of morbidity and mortality in the NICU, particularly among extremely preterm and/or chronically ill infants. Early recognition and diagnosis of LOS is challenging due to often non-specific presenting features and limited diagnostic efficiency of commonly used biomarkers.

  3. Nov 1, 2022 · Tools. Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

  4. Nov 11, 2022 · Late-onset sepsis is a significant cause of morbidity and mortality among very preterm infants, leading to high rates of empirical antibiotic administration for suspected infection.

  5. Introduction. Neonatal sepsis contributes substantially to neonatal morbidity and mortality, and is an ongoing major global public health challenge. 1 According to the onset of age, neonatal sepsis is divided into early-onset sepsis (EOS) and late-onset sepsis (LOS).

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