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      • LOS is primarily attributed to nosocomial or horizontal pathogen acquisition, and exposures to hospital or community environments. Pathogen exposure may occur due to contamination or colonization of indwelling invasive medical devices, contact with care providers, and/or other environmental sources and surfaces.
      www.ncbi.nlm.nih.gov › pmc › articles
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  2. Nov 11, 2022 · LOS is primarily attributed to nosocomial or horizontal pathogen acquisition, and exposures to hospital or community environments. Pathogen exposure may occur due to contamination or colonization of indwelling invasive medical devices, contact with care providers, and/or other environmental sources and surfaces.

  3. Nov 1, 2022 · Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

  4. Mar 31, 2021 · Introduction. Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It is associated with significant morbidity and mortality ( 1 – 3) that increase markedly when septic shock becomes established.

    • Carlota Gudiol, Adaia Albasanz-Puig, Adaia Albasanz-Puig, Guillermo Cuervo, Guillermo Cuervo, Jordi ...
    • 2021
  5. Jan 17, 2019 · Late onset sepsis (LOS) remains an important cause of neonatal morbidity and mortality. The presenting signs and symptoms are often subtle and mimic other neonatal conditions; however,...

  6. Neonatal sepsis contributes substantially to neo-natal morbidity and mortality, and is an ongoing major global public health challenge.1According to the onset of age, neonatal sepsis is divided into early-onset sepsis (EOS) and late-onset sepsis (LOS).

  7. Apr 18, 2024 · Interleukin-. 6 (IL-6) is a promising marker for neonatal sepsis. We aimed to test the accuracy of IL-6 in neonates after 72 h of life in case of late onset sepsis (LOS). We searched for studies regarding IL-6 accuracy for the diagnosis of LOS between 1990 and 2020 using the PubMed database.

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