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   How does the IARC select a carcinogenic agent?

   • The IARC staff makes the final selection of agents for review by taking into account the prevalence and intensity of exposure (of both occupational groups and the general population) and availability of sufficient literature for an evaluation of carcinogenicity, as well as advice from the Advisory Groups.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   Why did IARC create a list of agents that cause cancer?

   • Shortly after IARC’s establishment, its parent entity, the World Health Organization (WHO), asked IARC to prepare a list of agents known to cause cancer in humans. IARC recognized the need for a systematic process to determine which agents should be listed.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   What are IARC assessments of carcinogenicity based on?

   • IARC assessments of carcinogenicity are based on, and necessarily limited to, scientific evidence available at the time of the review. The evidence comes from epidemiologic studies, animal bioassays, pharmacokinetic/mechanistic experiments, and surveys of human exposure.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

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   What are IARC monographs used for?

   • IARC Monographs are widely used to identify potential carcinogenic hazards to humans and serve as reference documents summarizing the literature on many different agents.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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2. monographs.iarc.who.int › agents-classified-by-theAgents Classified by the IARC Monographs , Volumes 1–135

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   Dec 1, 2023 · Note: In September 2022, four additional individual Group 1 agents were created by splitting up some existing agent groupings because not all agents in the groups had the same cancer sites with sufficient and limited evidence for cancer in humans. Three strains of human papillomavirus (HPV) were split from a larger grouping of HPV strains.

3. www.iarc.who.int › infographics › iarc-monographsIARC Monographs hazard classification – IARC

   www.iarc.who.int › infographics › iarc-monographs

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   Jun 16, 2023 · This infographic presents the categories used by the IARC Monographs on the Identification of Carcinogenic Hazards to Humans to classify a substance according to the level of certainty that the substance can cause cancer.

4. monographs.iarc.who.int › human_cancer_knownHuman Cancer: Known Causes and Prevention by Organ Site

   monographs.iarc.who.int › human_cancer_known

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   Jan 23, 2024 · Human Cancer: Known Causes and Prevention by Organ Site. This poster presents the target organs for all agents classified as carcinogenic to humans (Group 1) by the IARC Monographs programme (in red text on the poster), and for the interventions showing sufficient evidence of a cancer-preventive effect in the IARC Handbooks of Cancer Prevention ...

5. www.ncbi.nlm.nih.gov › pmc › articlesIARC Monographs: 40 Years of Evaluating Carcinogenic Hazards ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Feb 24, 2015 · The IARC Monographs on the Evaluation of Carcinogenic Risks to Humans of the International Agency for Research on Cancer (IARC) are a prominent example of such an expert review process.

   • Author: Neil Pearce, Aaron Blair, Paolo Vineis, Wolfgang Ahrens, Aage Andersen, Josep M. Anto, Bruce K. Arms...

   • Publish Year: 2015

6. canceratlas.cancer.org › human-carcinogensHuman Carcinogens | The Cancer Atlas

   canceratlas.cancer.org › human-carcinogens

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   Sometimes called the WHO “Encyclopedia of Carcinogens,” the IARC Monographs are critical reviews and evaluations of the weight of the evidence that an agent can increase the risk of cancer in humans.

7. www.who.int › publications › mIARC Monographs on the Evaluation of Carcinogenic Risks to ...

   www.who.int › publications › m

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   Nov 14, 2012 · Volume 100 of the IARC Monographs, A Review of Human Carcinogens, covers all agents previously classified by IARC as "carcinogenic to humans (Group 1)" and was developed by six separate Working Groups: Pharmaceuticals; Biological agents; Arsenic, Metals, Fibres, and Dusts; Radiation; Personal Habits and Indoor Combustions; Chemical Agents and Re...