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What is pyrexia in Physiology?
What is fever & pyrexia?
Is pyrexia a sign of an infection?
What temperature should pyrexia be?
Sep 4, 2023 · Fever, or pyrexia, is the elevation of an individual's core body temperature above a 'set-point' regulated by the body's thermoregulatory center in the hypothalamus. This increase in the body's 'set-point' temperature is often due to a physiological process brought about by infectious causes or non-infectious causes such as inflammation ...
- The pathophysiological basis and consequences of fever - PMC
Fever has its etymological basis in Latin, meaning simply...
- Physiology, Fever - PubMed
Study Guide. Fever, or pyrexia, is the elevation of an...
- The pathophysiological basis and consequences of fever - PMC
- Temperature Target
- Efficacy and Risks of Antipyretic Methods
- Paracetamol
- Non-Steroidal Anti-Inflammatory Agents
- Surface Cooling Devices
- Endovascular Cooling Devices
- Thermal Tolerance of Cooling
Different approaches to fever treatment have been proposed: 1. Control of pyrexia when it occurs: treatment administered when temperature exceeds a predefined threshold 2. Strict avoidance of pyrexia: temperature maintained below fever threshold 3. Strict maintenance of normothermia: TTM with a predefined normothermia range, e.g., 36–37 °C. The abs...
Antipyretic agents, mainly paracetamol and NSAIDs, and physical cooling methods can be used to control pyrexia. Cooling with surface devices is usually preferred for fever control while endovascular methods are more commonly restricted to therapeutic hypothermia. Infusions of cold fluids are easy to administer and inexpensive but this strategy expo...
Paracetamol is the most commonly administered antipyretic in clinical practice . Compared with placebo or no treatment, the difference in body temperature usually reaches statistical significance, although this is modest with uncertain clinical significance. In patients with brain injury, a standard dose (3 g/day) of paracetamol is often reported a...
NSAIDs are regularly used in the ICU despite the lack of adequate safety evaluation. NSAIDs have a well known side effect profile including hypotension, impaired hepatic and renal function, sodium and water retention, gastrointestinal bleeding and platelet dysfunction. In an attempt to avoid some of these effects, low dose continuous infusion of di...
Three main types of surface cooling devices are available: air-circulating blankets, water circulating blankets and hydrogel-coated water-circulating pads . There is no evidence to support the use of fans for temperature control. Fans are usually considered to help with patient comfort but they can induce shivering . In febrile ICU patients, air-ci...
Several intravenous heat exchange catheter devices are available for temperature management . Endovascular cooling was initially evaluated for therapeutic hypothermia. Some controlled studies are now available in patients with acute brain injury managed with controlled normothermia. The obvious disadvantage is their associated risks, which are like...
Any decrease in core and/or peripheral temperature will result in vasoconstriction followed by shivering. In normal and febrile conditions, shivering commences at a body core temperature of ≈1.5 °C under the hypothalamic set point . Skin temperature accounts for around 20 % of thermoregulation and cold stress can promote shivering while the core te...
- James F. Doyle, Frédérique Schortgen
- 2016
Sep 1, 2016 · The definition of an elevated body temperature varies considerably by population and thermometer, and is commonly defined by a temperature of 38.0 °C or greater. Terms such as hyperthermia, pyrexia, and fever are often used interchangeably.
- Daniel J. Niven, Daniel J. Niven, Kevin B. Laupland
- 2016
Sep 11, 2023 · Fever is a physiological response that has persisted for hundreds of millions of years across species. How fever fights infection. Infections are caused by pathogens. Pathogens can be microbes ...
May 14, 2024 · Fever can be defined as any elevation of body temperature above the normal level. Persons with fever may experience daily fluctuations of 5–9 °F above normal; peak levels tend to occur in the late afternoon.
