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  1. The L5-S1 spinal motion segment, also called the lumbosacral joint, is the transition region between the lumbar spine and sacral spine in the lower back. In this region, the curvature of the spine changes from lumbar lordosis (forward curve) to sacral kyphosis (backward curve). L5-S1 helps transfer loads from the spine into the pelvis and legs.

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    Meredith Grey, Izzie Stevens, George O'Malley, Cristina Yang, and Alex Karev become interns at Seattle Grace Hospital. Meredith discovers that her one night stand was actually with one of her bosses and she and her new friends discover that being a surgeon isn't as easy or fun as they thought it would be.

    A woman wakes up from her couch, wraps a towel around her and begins to pick up her clothes. She throws a cushion on a man, who wakes up sleepily and passes her bra to her. The woman is embarrassed, and tells him to get dressed. They make small talk while he gets dressed. Apparently, she is going to be late on her first day of her new job. He compl...

    Main Cast

    1. Ellen Pompeo as Dr. Meredith Grey 2. Sandra Oh as Dr. Cristina Yang 3. Katherine Heigl as Dr. Izzie Stevens 4. Justin Chambers as Dr. Alex Karev 5. T.R. Knight as Dr. George O'Malley 6. Chandra Wilson as Dr. Miranda Bailey 7. James Pickens, Jr. as Dr. Richard Webber 8. Isaiah Washington as Dr. Preston Burke 9. Patrick Dempsey as Dr. Derek Shepherd

    Guest Stars

    1. Skyler Shaye as Katie Bryce 2. Randall Arney as Mr. Bryce 3. Kate Burton as Ellis Grey

    Co-Starring

    1. Robbie Troy as Mrs. Bryce 2. Moe Irvin as Tyler Christian 3. Lynn Marie Stewart as Nurse 4. Laura Carson as Gloria Savitch 5. Sean Palmer as Intern #3 6. Sendhil Ramamurthy as Intern #2 7. Richard Gilbert-Hill as Small Town Doc 8. Grinnell Morris as Intern #4 9. David Vegh as Tony Savitch 10. Kathleen M. Darcy as Anesthesiologist 11. Brad Pennington as Radiologist

    1. Diagnosis: 1.1. Aneurysm 1.2. Subarachnoid hemorrhage 1. Doctors: 1.1. Meredith Grey (surgical intern) 1.2. Derek Shepherd (neurosurgeon) 1.3. Cristina Yang (surgical intern) 1. Treatment: 1.1. Diazepam 1.2. Lorazepam 1.3. Phenobarbital 1.4. Aneurysm clip Katie Bryce, 15, was airlifted to Seattle Grace Hospitalafter having a grand mal seizure. Unable to discern the cause and unable to stop the seizures, Derek enlisted the help of the new interns, who were on their first shift, promising th...

    1. Diagnosis: 1. Doctors: 1.1. Preston Burke (cardiothoracic surgeon) 1.2. George O'Malley (surgical intern) 1. Treatment: 1.1. Coronary artery bypass surgery Tony Savitch was in the hospital to have bypass surgery. George promised him and his wife that he would be okay. However, in surgery, there were complications. He wasn't able to be taken off bypass and he died.

    Multiple Patients

    1. Diagnosis: 1. Doctors: 1.1. Izzie Stevens (surgical intern) 1. Treatment: Izzie did rectal exams on several patients.

    This episode's title originated from the song A Hard Day's Night, originally sung by The Beatles.
    This episode scored 16.25 million viewers.
    The part of the episode where Meredith urges Derek to leave the house after their one night stand almost didn't happen, as the ABC executives at the time found that nobody would care about a woman...
    Justin Chambers (Alex Karev) was not originally in the pilot. Scenes in which he appears were digitally altered or re-filmed.[source?]
    Meredith:We don't have to do the thing.
    Derek:We can do anything you want.
    Meredith:No, the thing. Exchange the details, pretend we care. Look, I'm gonna go upstairs and take a shower. Okay? And when I get back down here, you won't be here. So...um...goodbye...uh...
    Derek:Derek.
    Meredith:Derek! Right, Meredith.
  2. Mar 7, 2019 · Lumbarization of S1 or lumbarization of first sacral vertebra is a condition in which the first sacral vertebra is not completely attached to its fused sacral components but instead this first sacral vertebra appears like the other lumbar vertebrae.

  3. Mar 27, 2005 · A Hard Day's Night: Directed by Peter Horton. With Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers. The first shift for new surgical interns Meredith, Cristina, Izzie, George, and Alex proves eventful and backbreaking.

    • (3K)
    • Drama, Romance
    • Peter Horton
    • 2005-03-27
  4. The intensity of S1 depends upon: the position of the AV valves at the onset of ventricular systole, the structure of the leaflets themselves, and the rate of pressure rise in the ventricle. Normally, S1 is louder than S2 at the apex, and softer than S2 at the base of the heart.

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  6. The symptoms of S1 nerve compression, stemming from a herniated disc, can be diverse and often include lower back pain, sciatica, numbness, and weakness in the legs. Early recognition of these symptoms is crucial in preventing further S1 nerve damage and in initiating timely treatment.

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