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    what is are the earliest predictors 29 of neonatal sepsis death causes
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  1. www.ncbi.nlm.nih.gov › pmc › articlesInsight Into Neonatal Sepsis: An Overview - PMC

    Sep 19, 2023 · Peripheral blood smear (toxic granulation, vacuolization, and Dohle bodies) and leukocytic count are conventionally used in diagnosing neonatal sepsis [ 2 ]. Absolute neutrophilic count <1,000/mm 3 at ≥4 hours, i.e., neutropenia, is regarded as a precise indicator for early-onset neonatal sepsis [ 2 ].

    • 10.7759/cureus.45530
    • 2023/09
    • Cureus. 2023 Sep; 15(9): e45530.

  2. www.nature.com › articles › s41390/021/01696-zDiagnosis of neonatal sepsis: the past, present and future

    Nov 2, 2021 · Neonatal sepsis is still a major cause of morbidity and mortality despite advances in neonatal medicine. 4 Incidence varies from 1 to 4 cases per 1000 live births in high-income countries, but as ...

    • Istemi Han Celik, Morcos Hanna, Fuat Emre Canpolat, Fuat Emre Canpolat, Mohan Pammi
    • 2021

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  4. www.ncbi.nlm.nih.gov › books › NBK531478Neonatal Sepsis - StatPearls - NCBI Bookshelf

    Sep 29, 2022 · Elevated immature to total neutrophil (I/T)ratio of more than 0.27 has a very high negative predictive accuracy (99%) but an inadequate positive predictive value (25%) as it may be elevated in up to 50% of uninfected infants [14] [15]. These counts may be falsely elevated, especially after birth.

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29

  5. publications.aap.org › pediatrics › articleEarly-Onset Sepsis Among Very Preterm Infants | Pediatrics ...

    Oct 1, 2021 · Early-onset sepsis (EOS) is a significant cause of morbidity and mortality among newborn infants. The overall incidence of the disease in the US birth population is ∼1 case per 1000 live births but is ∼10-fold higher among infants born preterm. 1 For preterm infants at the lowest gestational ages (GAs), EOS-related mortality approaches 50%. 2 Because of this risk, ∼80% of very preterm ...

    • Dustin D. Flannery, Dustin D. Flannery, Erika M. Edwards, Karen M. Puopolo, Karen M. Puopolo, Jeffre...
    • 2021

  6. www.ncbi.nlm.nih.gov › pmc › articlesGlobal incidence and mortality of neonatal sepsis: a ...

    Jan 22, 2021 · We found in 26 studies a pooled neonatal sepsis incidence of 2824 sepsis cases per 100 000 live births (95% CI 1892 to 4194) and a mortality of 17.6% (95% CI 10.3% to 28.6%). Preterm and very low birthweight neonates were particularly affected, and there were considerable regional differences in incidence. Data are lacking from many countries ...

    • Carolin Fleischmann, Felix Reichert, Alessandro Cassini, Rosa Horner, Thomas Harder, Robby Markwart,...
    • 10.1136/archdischild-2020-320217
    • 2021
    • Arch Dis Child. 2021 Aug; 106(8): 745-752.

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  8. bmcpediatr.biomedcentral.com › articles › 10Prevalence and determinants of early onset neonatal sepsis at ...

    Jan 5, 2023 · Neonatal gestational age was also found to be a major predictor of neonatal sepsis with early onset. Early onset sepsis was three times more common in neonates born between 32 and 37 weeks gestational age (AOR: 3.2, 95% CI: 1.2—8.5) than in neonates born between 37 and 42 weeks gestational age.

  9. publications.aap.org › neoreviews › articleNeonatal Early-Onset Sepsis: Epidemiology and Risk Assessment

    Apr 1, 2015 · Neonatal early-onset sepsis (EOS) continues to be a significant source of morbidity and mortality among newborns, especially among very low-birth-weight infants. Epidemiologic risk factors for EOS have been defined, and considerable resources are devoted to the identification and evaluation of infants at risk for EOS. The widespread implementation of intrapartum antibiotic prophylaxis for the ...