Search results
Mar 30, 2023 · Dengue is a mosquito-borne infection caused by dengue virus (DENV) of the Flaviviridae family. There are four distinct serotypes, DENV-1,-2,-3,-4, which cause outbreaks globally. Infection is often self-resolving, and lifelong immunity against the infecting serotype can be achieved after exposure. However, in some individuals, homologous ...
- Antibody‐dependent enhancement (ADE) of dengue virus ...
Dengue virus (DENV) is an arbovirus transmitted mainly by...
- Current Understanding of the Pathogenesis of Dengue Virus ...
The pathogenesis of dengue virus infection is attributed to...
- Antibody‐dependent enhancement (ADE) of dengue virus ...
- What Is Ade?
- Is Ade Caused by A Disease?
- Is Ade Caused by Vaccines?
- Can The New Covid-19 Vaccines Cause Ade?
ADE occurs when the antibodies generated during an immune response recognize and bind to a pathogen, but they are unable to prevent infection. Instead, these antibodies act as a “Trojan horse,” allowing the pathogen to get into cells and exacerbate the immune response.
Most diseases do not cause ADE, but one of the best studied examples of a pathogen that can cause ADE is dengue virus. Dengue virus is one of the most common infections in the world, infecting hundreds of millions and killing tens of thousands of people each year. Unlike viruses like measles or mumps that only have one type, dengue virus has four d...
On a few occasions ADE has resulted from vaccination: 1. Respiratory syncytial virus (RSV) — RSV is a virus that commonly causes pneumonia in children. A vaccine was made by growing RSV, purifying it, and inactivating it with the chemical formaldehyde. In clinical trials, children who were given the vaccine were more likely to develop or die from p...
Neither COVID-19 disease nor the new COVID-19 vaccines have shown evidence of causing ADE. People infected with SARS-CoV-2, the virus that causes COVID-19, have not been likely to develop ADE upon repeat exposure. This is true of other coronaviruses as well. Likewise, studies of vaccines in the laboratory with animals or in the clinical trials in p...
People also ask
What are the symptoms of dengue?
What is severe dengue?
What causes severe manifestations of dengue virus disease?
May 14, 2024 · Symptoms of dengue can become severe within a few hours. Severe dengue is a medical emergency. About 1 in 20 people who get sick with dengue will develop severe dengue. Severe dengue can result in shock, internal bleeding, and death. Immediately go to a local clinic or emergency room if you or a family member has any of the following symptoms:
Oct 5, 2022 · Dengue (DENG-gey) fever is a mosquito-borne illness that occurs in tropical and subtropical areas of the world. Mild dengue fever causes a high fever and flu-like symptoms. The severe form of dengue fever, also called dengue hemorrhagic fever, can cause serious bleeding, a sudden drop in blood pressure (shock) and death.
The most widely known ADE example occurs with dengue virus. Dengue is a single-stranded positive-polarity RNA virus of the family Flaviviridae. It causes disease of varying severity in humans, from dengue fever (DF), which is usually self-limited, to dengue hemorrhagic fever and dengue shock syndrome, either of which may be life-threatening.
