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  2. A history of delivering preterm is one of the strongest predictors for subsequent preterm births. 1 Medically indicated preterm birth. If a serious medical condition—such as preeclampsia —exists, the health care provider might recommend a preterm delivery.

  3. Dec 1, 2022 · A cervix ≤25 mm measured by transvaginal ultrasound in the second trimester is considered short and predictive of an increased risk of preterm birth. Fetal fibronectin — A substance called fetal fibronectin is released when the fetal membranes begin to change prior to labor.

    • Data Source and Participants
    • Data Collection
    • Definition
    • Model Development and Validation
    • Sample Size and Model Power
    • Statistical Analysis

    Data used in this case-control study were extracted from the National Vital Statistics System (NVSS) database between 2018 and 2019 . The NVSS compiles the information from birth certificates and makes data files for each year, which is open access. The National Center for Health Statistics (NCHS) receives these electronic information files from th...

    Data of pregnant women were collected including age (< 35 years and ≥ 35 years), race (white, black, and others), education (high school or below, bachelor, and master or above), pre-pregnancy body mass index (BMI) (underweight, normal, overweight, and obesity), prenatal care (yes or no), pregnancy smoking (yes or no), pre-pregnancy diabetes (yes o...

    Preterm birth

    Preterm birth means births occurring before 37 completed weeks of gestation are preterm for purposes of classification consistent with the ICD-9 (International Classification of Diseases, Ninth Revision) and ICD-10 (International Classification of Diseases, Tenth Revision) definitions.

    Education

    Educational status was divided into three categories, high school or below, bachelor, and master or above. 8th grade or less, 9th through 12th grade with no diploma, high school graduate or GED completed, some college credit, but not a degree, associate degree (AA, AS) combined into high school and below. Master’s degree (MA, MS, MEng, MEd, MSW, MBA) and doctorate (PhD, EdD) or professional degree (MD, DDS, DVM, LLB, JD) merged into master’s degree and above.

    Pre-pregnancy BMI

    Pre-pregnancy BMI was calculated as: [mother’s pre-pregnancy weight (lb) / [mother’s height (in)]2] * 703 . Pre-pregnancy BMI: underweight (< 18.5 kg/m2), normal (18.5–24.9 kg/m2), overweight (25–29.9 kg/m2), obesity (≥30 kg/m2). In this study Obesity I: 30.0–34.9, Obesity II: 35.0–39.9, Obesity III: ≥40.0 combined into obesity (≥30 kg/m2).

    The 2019 data were randomly divided into the training set and testing set with a ratio of 1:1. Univariate and multivariate logistic regression analyses were conducted. Variables that were statistically significant in univariate analysis were included in multivariate analysis using backward stepwise regression. The odds ratio (OR) and 95% confidence...

    The sample size was calculated using the PASS 15.0.5 software (NCSS, LLC, Kaysville, UT, USA). Calculations of sample size and model power were shown in Supplement Fig. 1. The proportions of the general pregnant population who experienced age ≥ 35 (17.2%), pre-pregnancy underweight (6.0%), pregnancy smoking (5.2%), gestation diabetes (11.0%), gesta...

    Categorical variables were described in numbers and percentages [n (%)] and the groups were compared using χ2 tests or Fisher’s exact tests. SAS 9.4 software (SAS Institute Inc., Cary, NC, USA) was used for analysis. R 4.02 software (Institute for Statistics and Mathematics, Vienna, Austria) was used to draw logistic prediction model nomogram. Pyth...

  4. Introduction. Preterm birth (PTB) is defined as birth at < 37 weeks of gestation or at 259 days since the first day of woman's last menstrual period. It is classified into extremely preterm (PT) if <28 weeks, very PT if 28 to <33 weeks, and moderate PT if 34 to <37 completed weeks of gestation.

  5. Feb 7, 2021 · The main results of this study were: (1) At 24 weeks’ gestation, only 10% of women had CL < 26 mm; (2) The risk of PTB was inversely related to CL; (3) a CL < 26 mm at 24 weeks had a better predictive value compared to CL < 26 mm at 28 weeks (RR 6.1 vs. 5.3) for predicting PTB < 35 weeks.

    • Lee Reicher, Yuval Fouks, Yuval Fouks, Yariv Yogev, Yariv Yogev
    • 2021
  6. Feb 1, 2019 · The strongest predictor of preterm birth is a previous preterm birth or late miscarriage; these are associated with a 32% chance of a recurrent preterm birth [7]. Women with a previous preterm birth or late miscarriage, as well as those who have had previous cervical excisional surgery, are generally included in this group of asymptomatic women ...

  7. Protein-expression proteomics compares different proteomes to see how they vary – for example, comparing proteomes in a tumor versus adjacent normal tissue. Structural proteomics looks at the actual structure of proteins and groups proteins into families with similar structures.

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