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  1. Sep 25, 2023 · For over a decade, heart disease and cancer have claimed the first and second spots, respectively, as the leading causes of deaths in America. Together, the two causes are responsible for...

  2. Oct 6, 2023 · The Centers for Disease Control and Prevention (CDC) reports that 3.46 million people died in the US in 2021. Overall, 10 causes accounted for 74.5% of deaths that year. For comparison, the top 10 causes in 1999 accounted for approximately 80% of all deaths.

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    • Heart Disease. Number of deaths: 695,547. Rate: 173.8 per 100,000 population. Heart disease remained the top killer in the U.S. in 2021, accounting for about 20% of deaths even as its toll ticked down year over year by about 1,400 deaths.
    • Cancer. Number of deaths: 605,213. Rate: 146.6 per 100,000 population. The total number of cancer deaths in the U.S. increased by 2,863 in 2021, while the cancer death rate ticked up from 144.1 per 100,000 population in 2020.
    • COVID-19. Number of deaths: 416,893. Rate: 104.1 per 100,000 population. COVID-19 was the third-leading cause of death in the U.S. in 2021, surpassing the fourth-leading cause – unintentional injuries – by more than 190,000 deaths, as well as its 2020 toll by more than 66,000 deaths.
    • Accidents/Unintentional Injuries. Number of deaths: 224,935. Rate: 64.7 per 100,000 population. Unintentional injuries resulting from things like drug overdoses, car accidents and falls accounted for 6.5% of U.S. deaths in 2021.
  3. Jan 25, 2023 · Cardiovascular disease-related deaths jumped from 874,613 in 2019 to 928,741 in 2020, the largest single-year increase since 2015, according to the 2023 update to AHA's heart disease and stroke statistics, which was published Wednesday in Circulation.

  4. Explore interactive charts and maps of death rates in the United States and by state for national leading causes of death. See the top 15 causes of death for each state . Use our state-specific map to find cause-of-death statistics for each state.

  5. Jan 7, 2022 · COVID-19 was the 3 rd leading cause of death in 2020, with nearly 150,000 more deaths than the 4 th leading cause of death, accidents, and over 250,000 fewer deaths than the 2 nd leading cause of death, cancer. The final, official tally of COVID-19 deaths in the U.S. for 2020 was 350,831.

  6. Apr 22, 2022 · For the second year, COVID-19 was the third leading cause of death after heart disease and cancer. The second report shows that from 2020 to 2021, differences in COVID-19 death rates decreased among most racial and ethnic groups.

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