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   Will natural products contribute to drug development?

   • Overall, natural products will remain a major contributor to drug development and in our effort to curbing global health challenges as well as achieving sustainable development goals on health.

   The Role of Natural Products as Sources of Therapeutic Agents for

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8016209/

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   What drugs were discovered from natural products?

   • Many other drugs were discovered from natural products including tetracycline, artemisinin and doxorubicin. From the early days, plants extracts and concoctions were used as medicines but these are un-purified with little or no knowledge of which compounds within the extracts actually has healing powers.

   The Role of Natural Products as Sources of Therapeutic Agents for

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8016209/

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   Why are pharmaceutical medications made from natural products?

   • For ages, traditional medicines have depended on these natural products to treat many diseases. Today, most of the pharmaceutical medications are processed from these natural products. Natural products are made up of many bioactive compounds. These bioactive compounds impart biological activity against several disease-causing agents.

   Plant-derived natural products for drug discovery: current approaches

   www.ncbi.nlm.nih.gov/pmc/articles/PMC9579558/

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2. www.ncbi.nlm.nih.gov › pmc › articlesPlant-derived natural products for drug discovery: current...

   www.ncbi.nlm.nih.gov › pmc › articles

   Oct 18, 2022 · Nature has abundant source of drugs that need to be identified/purified for use as essential biologics, either individually or in combination in the modern medical field. These drugs are divided into small bio-molecules, plant-made biologics, and a recently introduced third category known as phytopharmaceutical drugs.

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     Nature has abundant source of drugs that need to be...

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     Nature has abundant source of drugs that need to be...

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     Natural Products as Sources of New Drugs over the Nearly...

3. www.nature.com › articles › s41573/020/00114-zNatural products in drug discovery: advances and opportunities

   www.nature.com › articles › s41573/020/00114-z

   Jan 28, 2021 · Historically, natural products (NPs) have played a key role in drug discovery, especially for cancer and infectious diseases 1, 2, but also in other therapeutic areas, including cardiovascular...

   • Author: Atanas G Atanasov, Sergey B Zotchev, Verena M Dirsch, Claudiu T Supuran

   • Publish Year: 2021

4. pubs.acs.org › doi › 10Natural Products as Sources of New Drugs over the Nearly Four ...

   pubs.acs.org › doi › 10

   A partial listing includes the following: endophytic and epiphytic microbes as sources of bioactive natural products; marine drug candidates; a chemometric analysis of the natural product drugs in the 2016 review versus synthetic drugs; a review of methods of “persuading” microbes to reveal their hidden genetic information; natural product ...

   • Author: David J. Newman, Gordon M. Cragg

   • Publish Year: 2020

5. www.ncbi.nlm.nih.gov › pmc › articlesThe Role of Natural Products as Sources of Therapeutic Agents ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jun 9, 2022 · The removal of potential bottlenecks resulting in minimal false positive leads in drug development has enabled an efficient system of drug discovery. This review describes the biosynthesis and screening of natural products during drug discovery as well as methods used in studying natural products.

   • Author: Kevin Dzobo

   • Publish Year: 2021

6. www.ncbi.nlm.nih.gov › pmc › articlesNatural products derived from plants as a source of drugs

   www.ncbi.nlm.nih.gov › pmc › articles

   The plant-derived compounds have a long history of clinical use, better patient tolerance and acceptance. To date, 35,000-70,000 plant species have been screened for their medicinal use. Plants especially those with ethnopharmacological uses have been the primary sources of medicine for early drug discovery.

   • Author: Ciddi Veeresham
   • DOI: 10.4103/2231-4040.104709

   • Publish Year: 2012
   • Published: Oct-Dec 2012

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8. theconversation.com › nature-is-the-worldsNature is the world’s original pharmacy – returning to ...

   theconversation.com › nature-is-the-worlds

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   Jul 27, 2022 · Cannabis. Fungi. Antibiotic resistance. Co-evolution. Cannabinoids. Drug discovery. Cannabidiol. Penicillin antibiotics. Antimicrobial agents. Natural products. COVID-19. Drug optimization....