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  1. Thus there are two major ascending pathways for pain: a direct lateral spinothalamic pathway and an indirect medial spinoreticulothalamic pathway. It is thought that the lateral pathway from the spinal cord to the ventrocaudal thalamus and to the cortex is responsible primarily for sharp, well-localized pains that arise near the body surface.

  2. Aug 1, 2014 · Basic Anatomy and Physiology of Pain Pathways. Keywords. Hyperalgesia. Allodynia. Peripheral sensitization. Spino-thalamic tract. Gait control theory. Descending systems. Key points. Introduction.

    • Sarah Bourne, Andre G. Machado, Sean J. Nagel
    • 2014
  3. May 5, 2018 · The pain pathways form a complex, dynamic, sensory, cognitive, and behavioral system that evolved to detect, integrate, and coordinate a pro-tective response to incoming noxious stimuli that threatens tissue injury or organism survival.1 This defense system includes both the primitive spinal reflexes that are the only protection for simple organ...

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